TYPE OF COURSE UNIT	Elective Course
LEVEL OF COURSE UNIT	Master's Degree With Thesis
YEAR OF STUDY	-
SEMESTER	-
NUMBER OF ECTS CREDITS ALLOCATED	10
NAME OF LECTURER(S)	-
LEARNING OUTCOMES OF THE COURSE UNIT	At the end of this course, the students; 1) Learn concepts of natural, synthetic, and semi-synthetic bioactive compounds, principles of extracting natural bioactive compounds, and biotechnology approaches in bioactive compound modification. 2) Understand basic strategies in development of targeted new molecules with known indications, biosimilar concept, good laboratory and manufacture practices. 3) Recognize strategies and applications from research and development phase to an authorized drug formulation.
MODE OF DELIVERY	Face to face
PRE-REQUISITES OF THE COURSE	No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT	No
COURSE DEFINITION
COURSE CONTENTS	WEEK TOPICS 1st Week 1. Introduction and Basic Concepts 2nd Week 2. concepts of natural, synthetic, and semi-synthetic bioactive compounds 3rd Week 3. principles of extracting natural bioactive compounds 4th Week 4. biotechnology approaches in bioactive compound modification Pharmaceutical Applications 5th Week 5. basic strategies in development of targeted new molecules with known indications 6th Week 6. Literature discussions 7th Week 7. biosimilar concept 8th Week 8. MIDTERM 9th Week 9. Drug Formulations 10th Week 10. GLP and GMP Concepts 11th Week 11. Phase Studies 12th Week 12. Patent Issues 13th Week 13. Recognition of Developed Drugs by Health Authorities 14th Week 14. Student presentations 15th Week
RECOMENDED OR REQUIRED READING	? Güncel literatür. / Update literature covering the studies in the area. ? Molecular Biotechnology, Principles and Applications of Recombinant DNA. Bernard R. Glick, Jack J. Pasternak, ASM Press, Washington, D.C., 2009.
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS	Lecture,Discussion,Questions/Answers,Presentation
ASSESSMENT METHODS AND CRITERIA	Quantity Percentage(%) Mid-term 1 35 Assignment 1 20 Total(%) 55 Contribution of In-term Studies to Overall Grade(%) 55 Contribution of Final Examination to Overall Grade(%) 45 Total(%) 100
ECTS WORKLOAD	Activities Number Hours Workload Midterm exam 1 84 84 Preparation for Quiz 1 16 16 Individual or group work 0 0 0 Preparation for Final exam 1 24 24 Course hours 14 3 42 Preparation for Midterm exam 1 11 11 Laboratory (including preparation) 0 0 0 Final exam 1 96 96 Homework 1 12 12 Project 1 12 12 Total Workload 297 Total Workload / 30 9,9 ECTS Credits of the Course 10
LANGUAGE OF INSTRUCTION	Turkish
WORK PLACEMENT(S)	No