At the end of this course, the students; 1) Knows Classification of Qualitative and Quantitative Analysis Methods. Knows the theoretical information that is important in the selection of the qualitative and quantitative Analysis Method of drugs from biological materials. Knows where the analyzes are used in the field of pharmacy and health. 2) Knows the biological materials and the preparation of drugs from biological materials for analysis. 3) Knows introduction to chromatography, introduction and classification of basic concepts. 4) Mathematical parameters in chromatography and are evaluated. 5) He / she can choose an appropriate chromatographic method in drug analysis from biological materials and know its application. 6) Knows the introduction and classification of spectroscopic methods and theoretical foundations of spectrophotometric methods. 7) Mathematical parameters in spectrophotometry and their evaluation Knows the appropriate spectroscopic method selection and application in drug analysis among biological materials. 8) Introduction to electrochemical methods and their classification, introduction of basic concepts of Electrochemical Methods.Mathematical parameters in electrochemistry and their evaluation.Knows the selection and application of the appropriate electrochemical method in drug analysis from biological materials. 9) Can use the information learned in this course in the business areas (industry) he / she works after graduation.
MODE OF DELIVERY
Face to face
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
None
COURSE DEFINITION
Theoretical bases and applications of qualitative and quantitative analysis of drugs from biological materials.
COURSE CONTENTS
WEEK
TOPICS
1st Week
Theoretical information about separation principles and separation methods
2nd Week
Liquid - solid consumption
3rd Week
Liquid - liquid consumption
4th Week
Definition, classification and theory of chromatography. Concepts, meanings and formulas in chromatography
5th Week
Planar chromatography (Thin layer and paper chromatography)
6th Week
Column chromatography
7th Week
Midterm exam
8th Week
Ion exchange chromatograph
9th Week
Gel chromatography and gas chromatography
10th Week
Gas chromatography
11th Week
Capillary electrophoresi
12th Week
High pressure liquid chromatography (HPLC)
13th Week
High pressure liquid chromatography (HPLC)
14th Week
Combined methods
RECOMENDED OR REQUIRED READING
1. A. Yıldız, Ö. Genç, S. Bektaş, Enstrümantal Analiz Yöntemleri, İkinci Baskı, Hacettepe Üniversitesi Yayınları, 1997. 2. D.A. Skoog, F.J. Holler, T.A. Nieman, Enstrümental Analiz İlkeleri, Bilim Yayıncılık, 2007. 3. H.H. Willard, L.L. Merritt, J.A. Dean, F.A. Settle, Instrumental Methods of Analysis, Sixth Edition, Litton Educational, USA, 1981. 4. D.A. Skoog, F.J. Holler, S.R. Crouch, Principles Instrumental Analysis, Sixth Edition, Brooks Cole, USA, 2006. 5. P. A. Sewell, B. Clarke, Chromatographic Separation, John Wiley & Sons, 1987. 6. OTHER RELATED RECENT GUIDES, PAPERS AND BOOKS
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
Lecture,Discussion,Problem Solving
ASSESSMENT METHODS AND CRITERIA
Quantity
Percentage(%)
Mid-term
1
35
Assignment
1
15
Total(%)
50
Contribution of In-term Studies to Overall Grade(%)
50
Contribution of Final Examination to Overall Grade(%)
50
Total(%)
100
ECTS WORKLOAD
Activities
Number
Hours
Workload
Midterm exam
1
1
1
Preparation for Quiz
0
0
0
Individual or group work
14
1
14
Preparation for Final exam
1
10
10
Course hours
14
2
28
Preparation for Midterm exam
1
5
5
Laboratory (including preparation)
0
0
0
Final exam
1
2
2
Homework
0
0
0
Total Workload
60
Total Workload / 30
2
ECTS Credits of the Course
2
LANGUAGE OF INSTRUCTION
Turkish
WORK PLACEMENT(S)
No
KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)
