At the end of this course, the students; 1) Learns the basic spectral methods used in the structure of organic compounds. 2) Evaluates the spectra obtained from these methods
MODE OF DELIVERY
Face to face
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
None
COURSE DEFINITION
Structure determination of drug active ingredients. Introduction to spectroscopy and basic principles. Ultraviyolet and visible spectroscopy. Infrared spectroscopy, Nuclear magnetic resonance spectroscopy, Mass spectroscopy.
COURSE CONTENTS
WEEK
TOPICS
1st Week
Structure determination of drug active ingredients
2nd Week
Introduction to spectroscopy and basic principles
3rd Week
Introduction to spectroscopy and basic principles
4th Week
Ultraviyolet and visible spectroscopy
5th Week
Infrared spectroscopy
6th Week
Infrared spectroscopy
7th Week
Midterm exam
8th Week
Nuclear magnetic resonance spectroscopy
9th Week
Nuclear magnetic resonance spectroscopy
10th Week
Nuclear magnetic resonance spectroscopy
11th Week
Nuclear magnetic resonance spectroscopy
12th Week
Nuclear magnetic resonance spectroscopy
13th Week
Mass spectroscopy
14th Week
Mass spectroscopy
RECOMENDED OR REQUIRED READING
1. Silverstein, R.M., Webster F. X., `Spectrometric Identification of Organic Compounds?, New York, 2005. 2. Ergenç, N., `İlaçların Tanınması ve Kalitatif Tayini? İstanbul, 1989. 3. Skoog, D.A., West D.M., `Principle of Instrumental Analysis? Philadelphia, 1980. 4. Willard H. H., Merritt L. L., Dean J. A., Seettle, F. A., `Instrumental Method of Analysis?, Belmont California (1988). 5. Pouchert, C.J., Behnke, J., The Aldrich Library of 13C and 1H FT-NMR Spectra, Aldrich Chemical, Milwaukee (1992) 6. Balcı M., `Nucleer Magnetic Rezonans Spektroskopisi?, Ankara 2000. 7. Williams, D.H., Fleming, I., Spectroscopic Methods in Organic Chemistry, London (1995). 8. Crews P., Rodriguez J, Jaspars M., Organic Structure Analysis, New York (1998). 9. Shriner R L., Hermann C., Morrill TC., Curtin DY., Fuson RC, The Systematic Identification of Organic Compounds (1999). 10. Hesse, M., Meier, H., Zeeh, B., Spectroscopic Methods in Organic Chemistry, Thieme, Stuttgart (2008).