TYPE OF COURSE UNIT	Compulsory Course
LEVEL OF COURSE UNIT	Bachelor's Degree
YEAR OF STUDY	4
SEMESTER	Eighth Term (Spring)
NUMBER OF ECTS CREDITS ALLOCATED	3
NAME OF LECTURER(S)	Professor Miyase Nilüfer Tarımcı Professor Fatma Nevin Çelebi
LEARNING OUTCOMES OF THE COURSE UNIT	At the end of this course, the students; 1) Learns the production of tablet formulations containing active pharmaceutical substances by wet granulation, dry granulation and direct compression techniques and quality control studies on the final product. 2) Learn the In Vitro Dissolution Testing for Solid Dosage Forms, and evaluate 3) Run accerelated stability tests on drugs and evaluate the data collected. 4) Learns to evaluate the results of bioavailability and bioequivalence studies on drugs. 5) Learn to understand Compatible / Incompatible Prescription problems encountered in magistral prescriptions. 6) Learns to apply the knowledge and skills gained in practical work in the field of health in the pharmacy, hospital pharmacy, and pharmaceutical industries. 7) Acquire knowledge about the rights and responsibilities, and act ethically and in compliance with regulations as an individual.
MODE OF DELIVERY	Face to face
PRE-REQUISITES OF THE COURSE	No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT	None
COURSE DEFINITION	ECZ 424 covers production and quality control of tablet dosage forms, eveluation of bioavailability and bioequivalence study results and information about incompatibilities encountered in prescriptions.
COURSE CONTENTS	WEEK TOPICS 1st Week Tablet production with wet granulation technique 2nd Week Tablet production with direct compression technique 3rd Week Tablet production with dry granulation technique 4th Week Quality control studies on tablets 5th Week In Vitro Dissolution Testing for Solid Dosage Forms 6th Week Evaluation and comment on In Vitro Dissolution Testing results 7th Week MID-TERM EXAMINATIONS 8th Week Aspirin stability study 9th Week Control Release Tablet formulation - Demonstration 10th Week Preparation of microsphere and nanoparticule - Demonstration 11th Week Bioavailability and bioequivalence Studies in drugs 12th Week Evaluation on Bioavailability and Bioequivalence studies results 13th Week Actual prescription samples 14th Week General evaluation 15th Week
RECOMENDED OR REQUIRED READING	1. Pharmaceutical Technology Laboratory workbook 2. Farmasötik Teknoloji Deneysel Uygulamalar Kitabı ? , Bozkır, A., Karataş, A., Hasçiçek, C., Canefe,C., Kılıçarslan, M., Tarımcı, N., Yüksel,N.,Gönül,N., Özdemir,N., Baykara, T., Kılınç-Şen, T., Çomoğlu, T.,A. Ü. Eczacılık Fakültesi Yayınları No: 95, Ankara Üniversitesi Basımevi, Ankara, (2007) 3. Ağabeyoğlu İ, Doğanay T, Çelebi N, Acartürk F, Ocak F, Ocak Ö, Değim T, Değim Z, Takka S, Türkyılmaz A., Teksin Z, Coşkun Ö, Uslu A, Yetkin G, Parlatan Z, Şenköylü A, İmren S, Sever S. Farmasötik Teknoloji - Laboratuvar El Kitabı, Ertem Matbaacılık, Ankara, 246 (1999). 4. Tırnaksız F., Karataş A., Akkuş- Arslan Ş., Tuğcu- Demiröz F., İlbasmış- Tamer S., Algan A.H., `Majistral İlaç Rehberi? Türk Eczacılar Birliği Yayınları, Ankara (2015) (Danışman Kurulu Üyeleri: Tarımcı N., Acartürk F., Çelebi N.)
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS	Lecture,Experiment
ASSESSMENT METHODS AND CRITERIA	Quantity Percentage(%) Mid-term 1 20 Assignment 3 5 Quiz 12 10 Practice 10 15 Total(%) 50 Contribution of In-term Studies to Overall Grade(%) 50 Contribution of Final Examination to Overall Grade(%) 50 Total(%) 100
ECTS WORKLOAD	Activities Number Hours Workload Midterm exam 1 2 2 Preparation for Quiz 14 1 14 Individual or group work 14 1 14 Preparation for Final exam 1 8 8 Course hours 0 0 0 Preparation for Midterm exam 1 3 3 Laboratory (including preparation) 14 3 42 Final exam 1 3 3 Homework 0 0 0 Report writing 14 1 14 Total Workload 100 Total Workload / 30 3,33 ECTS Credits of the Course 3
LANGUAGE OF INSTRUCTION	Turkish
WORK PLACEMENT(S)	No