TYPE OF COURSE UNIT	Compulsory Course
LEVEL OF COURSE UNIT	Bachelor's Degree
YEAR OF STUDY	4
SEMESTER	Seventh Term (Fall)
NUMBER OF ECTS CREDITS ALLOCATED	3
NAME OF LECTURER(S)	Professor Semra Kurucu Professor Arif Ahmet Başaran
LEARNING OUTCOMES OF THE COURSE UNIT	At the end of this course, the students; 1) The definition and classification of alkaloids due to amino acids, 2) The significant medicinal plants and their drugs containing alkaloids which are important in pharmacy and health system, methods for extraction and common analysis for qualitative and total quantitative determination of alkaloids from herbal materials, the evaluation of the results and the activities, toxicities and interactions of these herbal drugs, 3) Important alkaloids for health system, their physicochemical properties, separation and isolation methods, identification and quantification of the pure substances, their activities, safety usage and interactions, 4) Classical fermentation techniques, some examples from anibiotics, classical vaccines, blood products, herbal proteins and enzymes, the importance of cell culture methods in obtaining either new compounds or compound rich tissues. 5) The specifications of registered medicinal plants containing alkaloids and their drugs in various Pharmacopeias and monographs and the evaluation of the analysis from the point of conformity, 6) Noteworthy details of alkaloids for a safe and effective usage in health system, the risks and benefits of the end products, importance of following recent researches on investigations of new natural sources from the point of potential medicine 7) The importance of contribution of team studies in public health to warn public from unconscious and wrong applications in phytotherapy, homeopathy, transgenic plants and herbal teas.
MODE OF DELIVERY	Face to face
PRE-REQUISITES OF THE COURSE	No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT	Pharmaceutical Botany
COURSE DEFINITION	This lecture mainly depends on the identification of the nitrogen containing biological active compounds as well as the medicinal plants and the drugs containing these compounds. Besides the information of their quantification, efficacy and safely usage of these materials. correct and rational applications from the point of human health are also given.
COURSE CONTENTS	WEEK TOPICS 1st Week Introduction, Alkaloids: Definitions, Biogenesis,General properties,Classification 2nd Week Alkaloids Derived from Ornithine and lysine, tropane alkaloids 3rd Week Pyrrolizidine alkaloids, Quinolizidine Alkaloids, Indolizidin Alkaloids, Piperidine Alkaloids, alkaloids from nicotinic acid 4th Week Alkaloids derived from phenylalanine, and tyrosine, isoquinoline alkaloids, benzylisoquinolines and drugs 5th Week Bisbenzylisoquinolines -Curare alkaloids, Aporfinoids, protoberberine derivatives and drugs 6th Week Morphinan alkaloids and drugs 7th Week MID-TERM EXAM 8th Week Phenethylisoquinolines, Amaryllidaceae Alkaloids, Monoterpene Isoquinolines, Alkaloids derived from Tryptophan and drugs 9th Week Ergolin Alkaloids, Monoterpene Indole alkaloid and drugs 10th Week Rauwolfia alkaloids, Drugs containing Quinoline alkaloids 11th Week Alkaloids derived from Anthranilic Acid Alkaloids derived from Histidine and drugs 12th Week Terpene alkaloids, purine based compounds 13th Week Fermentation technology in Pharmacognosy, transgenic plants, classic vaccines 14th Week Herbal teas
RECOMENDED OR REQUIRED READING	1. Farmakognozi Cilt 1/2, Tanker M, Tanker N, Ankara Üniversitesi Eczacılık Fakültesi Yayınları. 2. Tyler VE, Brady LR, Robbers JE Pharmacognosy, Lea & Febriger, Philadelphia, 1981. 3. Jean Bruneton, Pharmacognosy, Phytochemistry, Medicinal Plants, Lavoisier Publishing Inc. c/o Springer-Verlag, New York, 1995. 4. R. Hansel, O. Sticher, E. Steinegger. Pharmakognosie ? Phytopharmazie. Springer-Verlag, Berlin 1999. 5. Trease and Evans Pharmacognosy, Saunders Elsevier, 16. Baskı, Philadelphia, 2009. 6. TF 7. FFD 8. DNotes (text and presentations).
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS	Lecture,Discussion,Presentation
ASSESSMENT METHODS AND CRITERIA	Quantity Percentage(%) Mid-term 1 25 Assignment 1 25 Total(%) 50 Contribution of In-term Studies to Overall Grade(%) 50 Contribution of Final Examination to Overall Grade(%) 50 Total(%) 100
ECTS WORKLOAD	Activities Number Hours Workload Midterm exam 1 1 1 Preparation for Quiz 0 0 0 Individual or group work 14 3 42 Preparation for Final exam 1 10 10 Course hours 14 2 28 Preparation for Midterm exam 1 5 5 Laboratory (including preparation) 0 0 0 Final exam 1 2 2 Homework 1 4 4 Article Presentation 1 4 4 Total Workload 96 Total Workload / 30 3,2 ECTS Credits of the Course 3
LANGUAGE OF INSTRUCTION	Turkish
WORK PLACEMENT(S)	No