At the end of this course, the students; 1) Learn the basic concepts of pharmacology, have knowledge about the pharmacokinetic and pharmacodynamic properties of drugs. 2) Gain knowledge of drug administration routes, mechanisms of action, factors that change drug effects, drug interactions, pharmacogenetics, rational drug use, drug abuse and addiction. 3) Learn the role of autocoids in physiological and pathological conditions and their use in therapy.
MODE OF DELIVERY
Face to face
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
None
COURSE DEFINITION
The aim of this lecture is to inform students about the basic pharmacological concepts, to provide information about the pharmacokinetic and pharmacodynamic properties of drugs, drug administration routes, mechanisms of action, factors that change drug effects, drug interactions, pharmacogenetics, rational drug use, drug abuse and addiction, the effects of autocoids in physiological and pathological processes and their use in treatment.
COURSE CONTENTS
WEEK
TOPICS
1st Week
Introduction to pharmacology
2nd Week
Drug administration routes
3rd Week
Drug Absorption and Distribution
4th Week
Metabolism and Elimination of Drugs
5th Week
Dose/concentration -response relationships
6th Week
Mechanisms of drug action
7th Week
Mid-term
8th Week
Receptors and drug-receptor interactions
9th Week
Factors that change drug effect and drug interactions
10th Week
Drug abuse and addiction
11th Week
Pharmacogenetics, Raational Drug Use
12th Week
Introduction to Autocoids
13th Week
Histamine and serotonin
14th Week
Prostaglandins, vasoactive substances and other autocoids
15th Week
Final
RECOMENDED OR REQUIRED READING
1. Kayaalp, S.O. Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Ankara, 2012 2. Kayaalp, S.O. Klinik Farmakolojinin Esasları ve Temel Düzenlemeler, 3.Baskı, 2005. 3. Goodman&Gilman The Pharmacological Basis of Therapeutics,The McGraw-Hill Company, 13th edition, 2017. 4. Katzung, B., Basic and Clinical Pharmacology, Appleton Lange, 14th edition. 2018. 5. Harvey, R.A. Lippincotts Illustrated Reviews: Pharmacology Wolters. Kluwer Lippincott Williams &Wilkins, 5th edition, 2012.
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
Lecture,Discussion
ASSESSMENT METHODS AND CRITERIA
Quantity
Percentage(%)
Mid-term
1
40
Total(%)
40
Contribution of In-term Studies to Overall Grade(%)
40
Contribution of Final Examination to Overall Grade(%)
60
Total(%)
100
ECTS WORKLOAD
Activities
Number
Hours
Workload
Midterm exam
1
1
1
Preparation for Quiz
0
0
0
Individual or group work
14
2
28
Preparation for Final exam
1
30
30
Course hours
14
3
42
Preparation for Midterm exam
1
20
20
Laboratory (including preparation)
0
0
0
Final exam
1
1
1
Homework
0
0
0
Total Workload
122
Total Workload / 30
4,06
ECTS Credits of the Course
4
LANGUAGE OF INSTRUCTION
Turkish
WORK PLACEMENT(S)
No
KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)