At the end of this course, the students; 1) To keep up to date with scientific information, the sources used in pharmaceutical technology (national, international books) will have information about pharmacopoeias. 2) Have knowledge about pharmacological basic processes such as grinding, mixing, filtering, drying and sterilization used in the preparation of drug formulations. 3) In the development of drug formulations; learns to plan and conduct the preformulation studies according to the physicochemical properties, stability and selection of the active substances acording to the drug forms. 4) In the development of drug formulations; learns to plan and conduct the preformulation studies according to the physicochemical properties, stability and drug form selection of the active substance. 5) Have knowledge about the ability to use the knowledge and skills gained in the advanced stages of education and to use them in professional life. 6) Acquire knowledge about duties, rights and responsibilities; and act ethically and in compliance with regulations as an individual.
MODE OF DELIVERY
Face to face
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
None
COURSE DEFINITION
ECZ321 covers sources in pharmaceutical technology, pharmacopoeias, unit processes (operations) used in preparations on drug formulations and preformulation studies, also stability knowledge for drugs, in order to follow the contemporary scientific information.
COURSE CONTENTS
WEEK
TOPICS
1st Week
Introduction to Pharmaceutical Technology, definition, history, pharmacopoeias and publications
2nd Week
Pharmaceutical water
3rd Week
Unit processes in Pharmaceutical Technology (grinding)
4th Week
Unit processes in Pharmaceutical Technology (drying,)
5th Week
Unit processes in Pharmaceutical Technology (mixing)
6th Week
Unit processes in Pharmaceutical Technology (filtration)
7th Week
MID TERM EXAMINATION
8th Week
Unit processes in Pharmaceutical Technology (filtration, sterilization)
9th Week
Colligative Properties (diffusion,osmosis)
10th Week
Preformulation (crystal properties and polymorphism)
11th Week
Preformulation (Physicochemical properties and particle size)
12th Week
Preformulation (Solid state characterization)
13th Week
Preformulation (Solubility, dissoltion rate and intrinsic dissolution)
14th Week
Preformulation (Stability of drugs)
RECOMENDED OR REQUIRED READING
1. Lecture notes 2. Modern Farmasötik Teknoloji, TEB Eczacılık Akademisi Yayını (Acartürk,F., Ağabeyoğlu,İ., Çelebi,N., Değim, T., Değim, Z.,Doğanay,T.,Takka,S., Tırnaksız,F.), 2007. 3. Farmasötik Teknoloji, Temel Konular ve Dozaj Şekilleri, Gürsoy, A., (Ed), İstanbul, I. Baskı, Kontrollü Salım Sistemleri Derneği Yayını No:2, 2004. 4. Physical Pharmacy (Editör: Alfred Martin) (Lea&Febriger, ABD, 1993.
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
Lecture,Discussion
ASSESSMENT METHODS AND CRITERIA
Quantity
Percentage(%)
Mid-term
1
40
Total(%)
40
Contribution of In-term Studies to Overall Grade(%)
40
Contribution of Final Examination to Overall Grade(%)
60
Total(%)
100
ECTS WORKLOAD
Activities
Number
Hours
Workload
Midterm exam
1
2
2
Preparation for Quiz
0
0
0
Individual or group work
14
2
28
Preparation for Final exam
1
12
12
Course hours
14
2
28
Preparation for Midterm exam
1
12
12
Laboratory (including preparation)
0
0
0
Final exam
1
3
3
Homework
1
6
6
Total Workload
91
Total Workload / 30
3,03
ECTS Credits of the Course
3
LANGUAGE OF INSTRUCTION
Turkish
WORK PLACEMENT(S)
No
KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)
