At the end of this course, the students; 1) know the extraction identification and quantitative methodss of volatile oils, volatile and nonvolatile secondary metabolites from medicinal plants and/or raw drugs important for human health. 2) learn the chromatographic and spectroscopic methods used for volatile oils and total secondary metabolites and gain the experience of analytic research. 3) Can perform purification and quantitation of individual natural secondary metabolites 4) know how to search the properties of volatile oils and secondary metabolites written in Pharmacopeia and monographs and bring the data as a report to authorities. 5) Have enough information on the safe and proper concentration and usage of the herbal preparations containing secondary metabolites and volatile oils used in phytotherapy, aronmatherapy and cosmetology.
MODE OF DELIVERY
Face to face
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
COURSE DEFINITION
Students experimentally learn the extraction methods, qualitative and quantitative methods for some important secondary metabolites in the given herbal medicine materials and compare the results with those of samples used in aromatherapy and phytotherapy theoretically. Analysis done with pharmacopeial methods will let them to get information on the requirements of herbal medicines for pharmaceutical usage.
COURSE CONTENTS
WEEK
TOPICS
1st Week
Detection of various herb powders with microscopy
2nd Week
Detection of various herb powders with microscopy
3rd Week
Total aldehyde determination in volatile oils and detection methods of vollatile oils.
4th Week
Quantitative determination of volatile oils by volumetric Pharmacopeia method and determination of water content in the material
5th Week
Quantitative determination of volatile oils by gravimetric Pharmacopeia method
6th Week
Gas chromatography analysis in voliatile oils (demonstrative)
Saponoside extraction and detection from the herbal medicine
10th Week
Cardioactive glycosides extraction and detection from herbal material
11th Week
Iridoid glycosides extraction and detection from herbal material
12th Week
Chromatographic application to separate terpenes in volatile oils
13th Week
Detection of unknown sample
14th Week
Discussion
RECOMENDED OR REQUIRED READING
1. Farmakognozi Cilt 1/2, Tanker M, Tanker N, Ankara Üniversitesi Eczacılık Fakültesi Yayınları. 2. Tyler VE, Brady LR, Robbers JE Pharmacognosy, Lea & Febriger, Philadelphia, 1981. 3. Trease and Evans Pharmacognosy, Saunders Elsevier, 16. Baskı, Philadelphia, 2009. 4. Sakar, K., Fitokimyasal Analiz, Ankara Üniversitesi Eczacılık Fakültesi yayınları, Ankara 1991. 5. Pharmacopeias
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
Lecture,Discussion,Experiment,Ödev
ASSESSMENT METHODS AND CRITERIA
Quantity
Percentage(%)
Quiz
10
15
Practice
10
40
Total(%)
55
Contribution of In-term Studies to Overall Grade(%)
55
Contribution of Final Examination to Overall Grade(%)
45
Total(%)
100
ECTS WORKLOAD
Activities
Number
Hours
Workload
Midterm exam
0
0
0
Preparation for Quiz
14
1
14
Individual or group work
14
2
28
Preparation for Final exam
1
12
12
Course hours
0
0
0
Preparation for Midterm exam
0
Laboratory (including preparation)
14
3
42
Final exam
1
2
2
Homework
0
0
0
Total Workload
98
Total Workload / 30
3,26
ECTS Credits of the Course
3
LANGUAGE OF INSTRUCTION
Turkish
WORK PLACEMENT(S)
No
KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)