At the end of this course, the students; 1) Learns the definition of secondary metabolites in plants, biosynthesis pathways, and their importance in pharmacy. 2) Recognize medicinal plants and drugs that carry important secondary metabolites in the field of pharmacy and health. Knows the diagnosis and quantification, effects, toxicities and interactions of total chemical substance groups (essential oil, total alcohol, iridoid, saponin, etc.) contained in drugs, makes analysis methods and evaluates the results. 3) Learns the physicochemical properties of essential volatile and non-volatile terpenes, aromatic compounds, sterols and steroidal structures in pharmacy, their chemical structures, isolation from natural sources, purification, diagnosis and quantification methods. Know their usage, interactions and usage doses, make analysis methods related to their activity and toxicity, follow the publications in this field and evaluate the results in terms of human health. 4) Knows the Pharmacopoeia and Monograph properties of the mentioned medicinal plants and drugs, and makes and evaluates the compatibility tests with appropriate methods. 5) Knows the issues to be considered in the preparation of phytotherapeutics and cosmeceuticals in which secondary metabolites take place. Follows the current scientific publications in the field of phytotherapy applications and other complementary medicine, and evaluates the situation in our country. 6) Based on the medicinal plants used by the people, he researches the new drug sources containing volatile and non-volatile substances scientifically and follows the publications. 7) Has a basic knowledge of aromatherapy and phytotherapy. Knows the points to be considered in rational aromatherapy applications. Contributes to teamwork in treatment and protection of public health. It warns and informs the society to prevent unconscious and wrong practices.
MODE OF DELIVERY
Face to face
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
Pharmaceutical Botany
COURSE DEFINITION
The lecture mainly consists of the scientific and recent information on natural secondary metabolites and some important medicinal plants and their drugs containing secondary metabolites, their identification and quantitation methods together with their safely usage in health system as well as the rational applications on these materials.
COURSE CONTENTS
WEEK
TOPICS
1st Week
Introduction, terpenoids: Definitions, Biogenesis, General properties
2nd Week
Volatile oils- General
3rd Week
Volatile oils: Monoterpenoids and monoterpenoid-containing drugs-1
4th Week
Volatile oils: Monoterpenoids and monoterpenoid-containing drugs-2
5th Week
Volatile oils: sequiterpenoids and sesquiterpenoid-containing drugs
6th Week
Drugs containing aromatic compounds, resins and resin-containing drugs
7th Week
MID-TERM EXAM
8th Week
Iridoids and iridoid-containing drugs.
9th Week
Sesquiterpenoid lactones and related drugs.
10th Week
Monoterpene alkaloids, sesquiterpene alkaloids and diterpene alkaloids
11th Week
Tetraterpenoids, Carotenoids, Other terpenes and steroids
12th Week
Triterpenes, steroidal triterpenes and related drugs
13th Week
Cardioactive glycosides and related drugs
14th Week
Saponins and related drugs
RECOMENDED OR REQUIRED READING
1. Farmakognozi Cilt 1/2, Tanker M, Tanker N, Ankara Üniversitesi Eczacılık Fakültesi Yayınları. 2. Tyler VE, Brady LR, Robbers JE Pharmacognosy, Lea & Febriger, Philadelphia, 1981. 3. Trease and Evans Pharmacognosy, Saunders Elsevier, 16. Baskı, Philadelphia, 2009. 4. Course notes (Text, presentation notes)
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
Lecture,Discussion
ASSESSMENT METHODS AND CRITERIA
Quantity
Percentage(%)
Mid-term
1
35
Assignment
1
15
Total(%)
50
Contribution of In-term Studies to Overall Grade(%)
50
Contribution of Final Examination to Overall Grade(%)
50
Total(%)
100
ECTS WORKLOAD
Activities
Number
Hours
Workload
Midterm exam
1
1
1
Preparation for Quiz
0
0
0
Individual or group work
14
3
42
Preparation for Final exam
1
12
12
Course hours
14
2
28
Preparation for Midterm exam
1
6
6
Laboratory (including preparation)
0
0
0
Final exam
1
2
2
Homework
1
12
12
Total Workload
103
Total Workload / 30
3,43
ECTS Credits of the Course
3
LANGUAGE OF INSTRUCTION
Turkish
WORK PLACEMENT(S)
No
KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)