At the end of this course, the students; 1) Learns oxidative phosphorylation and proton pump. 2) Comprehends alternative catabolic pathways for glucose. 3) Learns the basic features of amino acid catabolism. 4) YA Beta-oxidation, energy balance and regulation; learn ketone body synthesis. 5) Comprehends gluconeogenesis and its control. 6) Learns glycogen synthesis and degradation. Learns the synthesis of lipids. Understands protein synthesis and its control. Learns protein folding and posttranslational modifications. 7) Metabolic coordination; learns about neural and hormonal control mechanisms. Acquires basic information about signal transmission and secondary messengers. Review the metabolism.
MODE OF DELIVERY
Face to face
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
None
COURSE DEFINITION
Information is given about the biochemical synthesis and degradation pathways and the different control mechanisms in these pathways and the main metabolic pathways in humans.
COURSE CONTENTS
WEEK
TOPICS
1st Week
Oxidative phosphorylation and proton pump
2nd Week
Alternative catabolic pathways for glucose
3rd Week
Basic features of amino acid catabolism
4th Week
YA Beta-oxidation, energy balance and regulation
5th Week
Ketone body synthesis
6th Week
Gluconeogenesis and its control
7th Week
Midterm Exam
8th Week
Glycogen synthesis and degradation
9th Week
Synthesis of Lipids
10th Week
Protein synthesis and control
11th Week
Protein folding
12th Week
Posttranslational modifications
13th Week
Metabolic coordination; neural and hormonal control mechanisms
14th Week
Metabolic coordination; neural and hormonal control mechanisms; Metabolism
RECOMENDED OR REQUIRED READING
1. Stryer, L., Biochemistry, W.H. Freeman Company, New York, 2006. 2. Nelson,D.L.,Cox, M.M., Lehninger Principles of Biochemistry,Worth Publishers, 2006. 3. Bhagavan,N.V., Medical Biochemistry, Harcourt Academic Press, San Diego, 2002. 4. Guyton, A. C., Hall, E.J., Textbook of Medical Physiology, W.B. Saunders Company, Philadelphia, 2006. 5. Mathews, V.H. ,Holde, K.E. Biochemistry, The Benjamin Publish. Company, Redwood, 2000. 6. Alberts, B., Bray,D., Molecular Biology of the Cell, Garland Publ. Inc., New York, 2001. 7. Stites,D.P. Medical Immunology, Prentice Hall Int. Inc., London, 1997. 8. Murray, K.K., Granner, D.K., Harper?s Biochemistry, Appleton&Lange.
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
Anlatım,Tartışma
ASSESSMENT METHODS AND CRITERIA
Quantity
Percentage(%)
Mid-term
1
50
Total(%)
50
Contribution of In-term Studies to Overall Grade(%)
50
Contribution of Final Examination to Overall Grade(%)
50
Total(%)
100
ECTS WORKLOAD
Activities
Number
Hours
Workload
Midterm exam
1
1
1
Preparation for Quiz
0
0
0
Individual or group work
14
6
84
Preparation for Final exam
1
25
25
Course hours
14
2
28
Preparation for Midterm exam
1
15
15
Laboratory (including preparation)
0
0
0
Final exam
1
2
2
Homework
0
0
0
Total Workload
155
Total Workload / 30
5,16
ECTS Credits of the Course
5
LANGUAGE OF INSTRUCTION
Turkish
WORK PLACEMENT(S)
No
KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)