TYPE OF COURSE UNIT	Compulsory Course
LEVEL OF COURSE UNIT	Bachelor's Degree
YEAR OF STUDY	2
SEMESTER	Third Term (Fall)
NUMBER OF ECTS CREDITS ALLOCATED	3
NAME OF LECTURER(S)	Professor Selmuş Beniz Gündüz Professor Sacide Altınöz
LEARNING OUTCOMES OF THE COURSE UNIT	At the end of this course, the students; 1) Knows the definition of various instrument analysis methods. Makes qualitative and quantitative analysis of organic and inorganic materials with various chromatographic, spectroscopic and electrochemical methods. Gain knowledge and practical skills using various instrumental analysis methods. Learns how to make active substance (s) analysis from pharmaceutical preparations and drug and metabolite (s) analysis from biological materials (blood, urine, tissue etc.). 2) Knows general information about thin layer and column chromatography and makes qualitative analysis of drugs with this method. Analyzes some transition metal ion mixtures by ion exchange chromatography. 3) Knows the general information about ultraviolet - visible region (UV - GB) and derivative spectrophotometry methods and makes quantitative analysis of drugs and two-component mixtures with these methods. 4) Determination of complex formulas and stability constants by spectrophotometric method (JOB Method) 5) Knows general information about potentiometric titration and calculates the acidic equilibrium constants of a polyprotic acid with this method. 6) Knows general information about conductivity titration and makes quantitative analysis of strong and weak acids with this method. 7) Knows the validation parameters for method validity. 8) Makes application studies on the parameters related to validation through some articles and experiment. 9) After graduation, he can use the information he learned in this course in his work fields.
MODE OF DELIVERY	Face to face
PRE-REQUISITES OF THE COURSE	No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT	None
COURSE DEFINITION	Qualitative and quantitative analysis of organic and inorganic substances by various chromatographic, spectroscopic and electrochemical methods.
COURSE CONTENTS	WEEK TOPICS 1st Week Demonstration of spectroscopic, chromatographic and electrochemical methods 2nd Week Quiz and Qualitative analysis of drugs by thin layer chromatography at Week 2 3rd Week Quiz and Separation of indicator mixtures by column chromatography 4th Week Quiz and Analysis of some transition metal ion mixtures by Ion Exchange chromatography 5th Week Quiz and Quantitative analysis of drugs by UV-GB spectroscopy method (Paracetamol Quantitative Determination) 6th Week Quiz and Spectrophotometric quantification of two-component mixtures 7th Week Midterm exam week 8th Week Quiz and Analysis of two-component mixtures by derivative UV spectrophotometry 9th Week Quiz and Determination of complex formulas and stability constants by spectrophotometric method (JOB Method) 10th Week Quiz and Analysis of strong and weak acids by conductivity titration 11th Week Quiz and Determination of acidity equilibrium constants of a polyprotic acid by potentiometric titration 12th Week Validation demonstration 13th Week Practical studies on parameters related to validation through some articles and experiments 14th Week Quiz and Discussion of validation assignments
RECOMENDED OR REQUIRED READING	1. D.A. Skoog, F.J. Holler, S.R. Crouch, Principles Instrumental Analysis, Sixth Edition, Brooks Cole, USA, 2016. 2. H.H. Willard, L.L. Merritt, J.A. Dean, F.A. Settle, Instrumental Methods of Analysis, Sixth Edition, Litton Educational, USA, 1981. 3. OTHER RELATED CURRENT GUIDES, ARTICLES AND BOOKS
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS	Lecture, Discussion, Report Preparation and/or Presentation, Experiment
ASSESSMENT METHODS AND CRITERIA	Quantity Percentage(%) Assignment 1 10 Quiz 10 10 Practice 9 30 Total(%) 50 Contribution of In-term Studies to Overall Grade(%) 50 Contribution of Final Examination to Overall Grade(%) 50 Total(%) 100
ECTS WORKLOAD	Activities Number Hours Workload Midterm exam 0 0 0 Preparation for Quiz 10 1 10 Individual or group work 14 2 28 Preparation for Final exam 1 8 8 Course hours 0 0 0 Preparation for Midterm exam 0 0 0 Laboratory (including preparation) 14 3 42 Final exam 1 2 2 Homework 1 4 4 Quiz 10 ,25 2,5 Total Workload 96,5 Total Workload / 30 3,21 ECTS Credits of the Course 3
LANGUAGE OF INSTRUCTION	Turkish
WORK PLACEMENT(S)	No