At the end of this course, the students; 1) the general properties, structure, classification of bacteria, fungi, parasites, viruses; the differences between microorganisms; bacterial metabolism, mechanisms of genetic transfer between bacterial cells will be mentioned. host-microorganism relationships, normal flora of the body, transmission routes of microorganisms and medically important bacteria, fungi, parasites and viruses. 2) the mechanisms of action of antimicrobial agents, mechanisms of antimicrobial resistance and the concepts of sterilization, disinfection, antisepsis. 3) support the theoretical information by microbiology laboratory practices.
MODE OF DELIVERY
Face to face 50% + E-Learning 50%
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
None
COURSE DEFINITION
Basic principles of microbiology, general characteristics, structure and differences of microorganisms (bacteria, viruses, fungi, parasites), classification, mechanisms of genetic information exchange in bacteria, bacterial metabolism, host-microorganism relations, transmission routes, normal flora of the body, microorganisms with medical importance, antimicrobial mechanisms of action of agents, mechanisms of resistance to antimicrobials; In addition, it provides students with knowledge about the concepts of sterilization, disinfection and antisepsis. In addition, practical applications are provided to students in microbiology laboratory procedures.
COURSE CONTENTS
WEEK
TOPICS
1st Week
Introduction to Microbiology, Biosafety applications; Use of PPE, Sterilization, disinfection, medical wastes, Biosafety applications; Use of PPE, Sterilization, disinfection, medical waste
2nd Week
Host-microorganism relationship, transmission routes and virulence, Normal body flora, General characteristics of bacteria (Bacterial structure), LAB: Microbiology laboratory rules, devices and materials used in the laboratory
3rd Week
General characteristics of bacteria (Production, metabolism and staining methods of bacteria), General characteristics of bacteria (Bacterial genetics), Gram positive cocci, LAB: Devices and materials used in the laboratory
4th Week
Gram positive bacilli, Anaerobic bacteria, Enterobacterales, LAB: Staining methods and microscopy of bacteria
5th Week
Aerobic gram-negative cocci and coccobacilli, Non-fermentative bacteria, Vibrionaceae, Aeromonas, Campylobacter-Helicobacter genus, LAB: Media, cultivation methods and colony morphologies
6th Week
Mycobacteria (Mycobacterium tuberculosis complex, M.leprae), Treponemas, Borrelia, Leptospira, Rickettsialar, Chlamydia, Mycoplasma and Ureaplasma, LAB: Examination of Gram positive bacteria
7th Week
Antibiotics and their mechanisms of action, Antibiotic resistance mechanisms, General characteristics of viruses - 1, LAB: Examination of Gram positive bacteria
8th Week
General characteristics of viruses - 2, DNA viruses, RNA viruses-I, LAB: Examination of gram negative bacteria
Antivirals and their mechanisms of action, Resistance mechanisms to antivirals, General characteristics and classification of parasites, LAB: Examination of bacteria with different characteristics
Helminths, Arthropods and vector-borne agents, Antiparasitic agents, LAB: Diagnostic methods in virology
13th Week
General characteristics and classification of fungi, Superficial and cutaneous mycoses, Subcutaneous and systemic mycoses, LAB: Investigation of Parasites
14th Week
Opportunistic mycoses, Antifungal agents and resistance mechanisms, General review, LAB: A Study of Fungi
RECOMENDED OR REQUIRED READING
1. Medical Microbiology. Murray P.R, Rosenthal K.S, Kobayashi G.S, Pfaller M.A.(Eds) Mosby Inc. 2002, Fourth Ed. St. Louis. ISBN: 0-323-01213-2. 2. Microbiology. Tortora G.J, Funke B.R, Case C.L (Eds.) Addison Wesley Longman Inc. 2010. 10th Ed. Toronto. ISBN 0-8053-7543-0
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
Experiment,Lecture,Discussion
ASSESSMENT METHODS AND CRITERIA
Quantity
Percentage(%)
Mid-term
1
50
Total(%)
50
Contribution of In-term Studies to Overall Grade(%)
50
Contribution of Final Examination to Overall Grade(%)
50
Total(%)
100
ECTS WORKLOAD
Activities
Number
Hours
Workload
Midterm exam
1
1
1
Preparation for Quiz
0
0
0
Individual or group work
14
6
84
Preparation for Final exam
1
30
30
Course hours
14
3
42
Preparation for Midterm exam
1
20
20
Laboratory (including preparation)
0
0
0
Final exam
1
2
2
Homework
0
0
0
Total Workload
179
Total Workload / 30
5,96
ECTS Credits of the Course
6
LANGUAGE OF INSTRUCTION
Turkish
WORK PLACEMENT(S)
No
KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)