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COURSE UNIT TITLECOURSE UNIT CODESEMESTERTHEORY + PRACTICE (Hour)ECTS
NUCLEIC ACID AND PROTEIN CHEMISTRY BTE501 First Term (Fall) 3 + 0 10

TYPE OF COURSE UNITCompulsory Course
LEVEL OF COURSE UNITMaster's Degree With Thesis
YEAR OF STUDY1
SEMESTERFirst Term (Fall)
NUMBER OF ECTS CREDITS ALLOCATED10
NAME OF LECTURER(S)-
LEARNING OUTCOMES OF THE COURSE UNIT At the end of this course, the students;
1) Learns bonding structures of organic molecules.
2) Learns molecular structures and functions of nucleic acids and proteins.
3) Understands physiology of different cell types while evaluating structural information in terms of molecular evolution.
4) Learn to use structural knowledge for cellular modifications.
MODE OF DELIVERY
PRE-REQUISITES OF THE COURSENo
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
COURSE DEFINITIONThe aim of this course is to make students to learn and discuss the bonding structures of organic molecules, the structure of nucleic acids and protein molecules, Watson-Crick model of DNA, structure and types of RNA, transcription, translation, 3-D structure of proteins; to understand and discuss the methods for investigating nucleic acids and proteins such as Scanning Force Microscopy (SFM), High Pressure Liquid Chromatography (HPLC), Isoelectric Focusing (IeF), 3D Gel Electrophoresis, SDS Denaturation, Bradford Test. This course aims to provide students with a biological perspective. At the end of the course the students are also expected to understand physiology of different cell types while evaluating structural information in terms of molecular evolution and to use structural knowledge for cellular modifications.
COURSE CONTENTS
WEEKTOPICS
1st Week 1 Introduction
2nd Week 2 Atoms, molecules and their interactions
3rd Week 3 Building blocks of DNA: nucleic acids
4th Week 4 Physical and chemical properties of nucleic acids
5th Week 5 Physical and chemical properties of proteins
6th Week 6 Watson and Crick's model of DNA
7th Week 7 Midterm Exam
8th Week 8 Highly organized structure of DNA
9th Week 9 Structure of RNA
10th Week 10 Types of RNA
11th Week 11 Transcription and Translation
12th Week 12 Amino acids and 3D-structures of proteins
13th Week 13 Examination methods of nucleic acids and proteins (SFM, HPLC, IeF, 3D Gel Electrophoresis, SDS Denaturing Gel, Bradford Protein Assay)
14th Week 14 Project Presentation - Final Examination
15th Week
RECOMENDED OR REQUIRED READINGLehninger Principles of Biochemistry 7th Edition, Albert L. Lehninger ve David L. Nelson
PLANNED LEARNING ACTIVITIES AND TEACHING METHODSLecture,Discussion,Questions/Answers,Project
ASSESSMENT METHODS AND CRITERIA
 QuantityPercentage(%)
Mid-term120
Project130
Attendance120
Total(%)70
Contribution of In-term Studies to Overall Grade(%)70
Contribution of Final Examination to Overall Grade(%)30
Total(%)100
ECTS WORKLOAD
Activities Number Hours Workload
Midterm exam18484
Preparation for Quiz11616
Individual or group work000
Preparation for Final exam12424
Course hours14342
Preparation for Midterm exam11111
Laboratory (including preparation)000
Final exam19696
Homework11212
Project11212
Total Workload297
Total Workload / 309,9
ECTS Credits of the Course10
LANGUAGE OF INSTRUCTION
WORK PLACEMENT(S)No
  

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