At the end of this course, the students; 1) Learns bonding structures of organic molecules. 2) Learns molecular structures and functions of nucleic acids and proteins. 3) Understands physiology of different cell types while evaluating structural information in terms of molecular evolution. 4) Learn to use structural knowledge for cellular modifications.
MODE OF DELIVERY
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
COURSE DEFINITION
The aim of this course is to make students to learn and discuss the bonding structures of organic molecules, the structure of nucleic acids and protein molecules, Watson-Crick model of DNA, structure and types of RNA, transcription, translation, 3-D structure of proteins; to understand and discuss the methods for investigating nucleic acids and proteins such as Scanning Force Microscopy (SFM), High Pressure Liquid Chromatography (HPLC), Isoelectric Focusing (IeF), 3D Gel Electrophoresis, SDS Denaturation, Bradford Test. This course aims to provide students with a biological perspective. At the end of the course the students are also expected to understand physiology of different cell types while evaluating structural information in terms of molecular evolution and to use structural knowledge for cellular modifications.
COURSE CONTENTS
WEEK
TOPICS
1st Week
1 Introduction
2nd Week
2 Atoms, molecules and their interactions
3rd Week
3 Building blocks of DNA: nucleic acids
4th Week
4 Physical and chemical properties of nucleic acids
5th Week
5 Physical and chemical properties of proteins
6th Week
6 Watson and Crick's model of DNA
7th Week
7 Midterm Exam
8th Week
8 Highly organized structure of DNA
9th Week
9 Structure of RNA
10th Week
10 Types of RNA
11th Week
11 Transcription and Translation
12th Week
12 Amino acids and 3D-structures of proteins
13th Week
13 Examination methods of nucleic acids and proteins (SFM, HPLC, IeF, 3D Gel Electrophoresis, SDS Denaturing Gel, Bradford Protein Assay)
14th Week
14 Project Presentation - Final Examination
15th Week
RECOMENDED OR REQUIRED READING
Lehninger Principles of Biochemistry 7th Edition, Albert L. Lehninger ve David L. Nelson
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
Lecture,Discussion,Questions/Answers,Project
ASSESSMENT METHODS AND CRITERIA
Quantity
Percentage(%)
Mid-term
1
20
Project
1
30
Attendance
1
20
Total(%)
70
Contribution of In-term Studies to Overall Grade(%)
70
Contribution of Final Examination to Overall Grade(%)
30
Total(%)
100
ECTS WORKLOAD
Activities
Number
Hours
Workload
Midterm exam
1
84
84
Preparation for Quiz
1
16
16
Individual or group work
0
0
0
Preparation for Final exam
1
24
24
Course hours
14
3
42
Preparation for Midterm exam
1
11
11
Laboratory (including preparation)
0
0
0
Final exam
1
96
96
Homework
1
12
12
Project
1
12
12
Total Workload
297
Total Workload / 30
9,9
ECTS Credits of the Course
10
LANGUAGE OF INSTRUCTION
WORK PLACEMENT(S)
No
KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)