At the end of this course, the students; 1) Will be able to discuss the morphological structures and the locations of the components of the gastrointestinal system, general structure of the abdominal wall and the abdominal cavity and to discus their disorders related with physioanatomy. 2) Will be able to associate the functional interaction between gastrointestinal system, endocrine system and nervous system; to be able to describe mechanisms underlying gastrointestinal motor and secretory functions and to incorporate them into clinical skills in the future. 3) Will be able to recognize and evaluate structural features of cells, tissues and organs belonging to digestive system and associated glands and their role in the human body, to distinguish the cells, tissues and organs of this system by self examination under light microscope and to presume and correlate the reasons of abnormal development of this system and the underlying mechanisms knowing the basic elements of normal development 4) Will be able to interpret the cellular and metabolic responses in extreme conditions of nutrition 5) Will be able to describe the regulatory role of related hormons 6) Will be able to explain digestion and absorption of basic biological molecules, their metabolisms, interrelationships of metabolism and inborn errors of metabolism. 7) Will be able to use certain methods of statistics in health sciences
MODE OF DELIVERY
Face to face
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
The entire curriculum of the academic year
COURSE DEFINITION
This course reviews the basic principles related to anatomy, histology-embryology, physiology, genetic and biochemistry of gastrointestinal system and metabolism. This course also reviews the basic concepts and nature of statistical problems
COURSE CONTENTS
The main objectives of the course are to familiarize students with the morphology of the gastrointestinal system and to make them ready to understand their functions and to discuss the basic disorders related with anatomy, to describe the histological structure of digestive system and associated glands, to help students to understand to inform students about functions of digestive system including motility, secretion, digestion and absorption and also to enable students to comprehend the interaction between gastrointestinal system, endocrine system and nervous system, to explain digestion and absorption of basic biological molecules, their metabolisms, interrelationships of metabolism and inborn errors of metabolism. Additionally, students familiarize with parametric tests, correlation and linear regression analysis.
RECOMENDED OR REQUIRED READING
1. Taner D (2008) Fonksiyonel Anatomi: Ekstremiteler ve Sırt Bölgesi, Ankara: PALME 2. Snell RS (1998) Clinical Anatomy for Medical Students, Washington: Lippincot-Williams&Wilkins 3. Guyton, AC, Hall, JE (2006) Textbook of Medical Physiology, Pennsylvania:WB Saunders, Eleventh ed. 4. Ganong, WF (2003) Review of Medical Physiology, USA:Mc Graw Hill,Twentieth edition.? Conwey ? Spector 5. Küehnel, Wolfgang. (2003). Color Atlas of Cytology, Histology, and Microscopic Anatomy. Stuttgart ? New York: Thieme Verlack 6. Fawcett, Don W. (1994). A Textbook of Histology. New York ? London: Chapman and Hall. Twelfh Edition 7. Medical Biochemistry-Baynes and Dominiczak, 2008 8. Textbook of Biochemistry with Clinical Correlations-Devlin, 2011 9. Gardner Shoback Greenspan?s Basic and Clinical Endocrinology ,2011 10. Nelson DL and Cox MM 2013, Lehninger Principles of Biochemistry. Fifth Edition, W.H. Freeman and Company, NY; USA. 11. Lewis R., 2001 ?Human Genetics, Concepts and Applications? Mc Graw Hill New York. BIOSTATISTICS 1) Biometry: The Principles and Practice of Statistics in Biological Research, Sokal R. R., Rohlf F. J., 3rd edition, W. H. Freeman & Co. 2) Bioistatistics, A Foundation for Analysis in the Health Sciences, Wayne W. D., John Wiley & Sons Inc., 1995. 3) Biyoistatistik, Kesici T., Kocabaş Z., Ankara Üniversitesi Eczacılık Fakültesi Yayınları, 1998. 4) Biyoistatistik. Sümbüloğlu, K., Sümbüloğlu, V., Özdemir Yayıncılık, Ankara, 1995. 5) İstatistik Metodları. Düzgüneş, O., Kesici,T., Gürbüz, F., A.Ü. Ziraat Fakültesi Yayınları, Ankara,1983. 6) Statistics for Experimenters, An Introduction to Design, Data Analysis, and Model Building, Box, E.P.G., Hunter, G.W., Hunter, J. S.,John Wiley & Sons,Inc., 1978. 7) Statistical Methods, Snedecor, G. W., Cochran,W. G., The Iowa State University Press, 1980. 8) Statistics with Applications to the Biological and Health Sciences, M. Anthony Schork, Richard D. Remington, Prentice Hall, 2000. 9) Reha Alpar, Uygulamalı İstatistik ve Geçerlik Güvenirlik, 2016, Detay Yayıncılık. 10) Kazım Özdamar, Ölçek ve Test Geliştirme, Yapısal Eşitlik Modellemesi, Nisan Yayınevi, 2016. 11) Dawson B., Trapp R.G., Basic and Clinical Biostatistics. 2004, McGraw-Hill Companies Inc. Newyork, USA. 12) Özdamar K. SPSS ile Biyoistatistik. Genişletilmiş Beşinci Baskı, 2003, Kaan Kitapevi 13) Alpar R., Spor, Sağlık ve Eğitim Bilimlerinden Örneklerle, Uygulamalı İstatistik ve Geçerlik- güvenirlik, 2010, Detay Yayıncılık.
