TYPE OF COURSE UNIT	Elective Course
LEVEL OF COURSE UNIT	Master's Degree With Thesis
YEAR OF STUDY	-
SEMESTER	-
NUMBER OF ECTS CREDITS ALLOCATED	10
NAME OF LECTURER(S)	-
LEARNING OUTCOMES OF THE COURSE UNIT	At the end of this course, the students; 1) Know how to evaluate bioreactor operation mode alternatives, build a mathematical model to be used in bioreactor design, and prepare an experimental execution plan. 2) Know how to analyze bioreactor experimental execution results using informatics technologies, and calculate optimum values for system parameters using mathematical modeling. 3) Know how to evaluate purification method alternatives, carry out accelerated shelf-life testing study, and prepare design outputs in report or presentation format using informatics technologies.
MODE OF DELIVERY	Face to face
PRE-REQUISITES OF THE COURSE	No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT	Biotechnology
COURSE DEFINITION	In this course, bioengineering approaches in molecular biology are explained discussing bioreactor/fermenter design/scale-up, sterilization/thermal death kinetics of microorganisms, kinetics of biological reactions, enzyme kinetics, immobilized biocatalysts, kinetics of microbial growth, batch versus continuous operations, heat transfer/mass transfer in bioprocessing, product recovery/downstream processing, and bioprocess economics.
COURSE CONTENTS	WEEK TOPICS 1st Week Bioengineering approaches in molecular biology 2nd Week Bioreactor/fermenter design/scale-up 3rd Week Sterilization/thermal death kinetics of microorganisms 4th Week Kinetics of biological reactions 5th Week Enzyme kinetics 6th Week Immobilized biocatalysts 7th Week Kinetics of microbial growth 8th Week Midterm Exam 9th Week Batch versus continuous operations 10th Week Heat transfer/mass transfer in bioprocessing 11th Week Heat transfer/mass transfer in bioprocessing 12th Week Product recovery/downstream processing 13th Week Product recovery/downstream processing 14th Week Bioprocess economics
RECOMENDED OR REQUIRED READING	Kim Gail Clarke, 2013, Bioprocess Engineering: An Introductory Engineering and Life Science Approach, Woodhead Publishing
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS	Lecture,Discussion,Questions/Answers,Case Study,Project,Report Preparation,Presentation
ASSESSMENT METHODS AND CRITERIA	Quantity Percentage(%) Mid-term 1 35 Project 1 25 Total(%) 60 Contribution of In-term Studies to Overall Grade(%) 60 Contribution of Final Examination to Overall Grade(%) 40 Total(%) 100
ECTS WORKLOAD	Activities Number Hours Workload Midterm exam 1 2 2 Preparation for Quiz Individual or group work Preparation for Final exam 1 100 100 Course hours 14 3 42 Preparation for Midterm exam 1 90 90 Laboratory (including preparation) Final exam 1 2 2 Homework Project 1 65 65 Total Workload 301 Total Workload / 30 10,03 ECTS Credits of the Course 10
LANGUAGE OF INSTRUCTION	English
WORK PLACEMENT(S)	No