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COURSE UNIT TITLECOURSE UNIT CODESEMESTERTHEORY + PRACTICE (Hour)ECTS
MOLECULAR EVOLUTION MBGE502 - 3 + 0 10

TYPE OF COURSE UNITElective Course
LEVEL OF COURSE UNITMaster's Degree With Thesis
YEAR OF STUDY-
SEMESTER-
NUMBER OF ECTS CREDITS ALLOCATED10
NAME OF LECTURER(S)Assistant Professor Çiğdem Akın Pekşen
LEARNING OUTCOMES OF THE COURSE UNIT At the end of this course, the students;
1) Learn the basis of evolution at molecular and population.
2) Learn the concepts of DNA and protein evolution and rate and pattern of molecular evolution.
3) Learn molecular phylogenetic approaches and their applications.
4) Learn how evolution takes place by means of gene duplications, molecular tinkering and mobile elements.
5) Learn the mechanisms of prokaryotic and eukaryotic genom evolution and gene regulation.
MODE OF DELIVERYFace to face
PRE-REQUISITES OF THE COURSENo
RECOMMENDED OPTIONAL PROGRAMME COMPONENTMolecular Genetics,Evolutionary Biology
COURSE DEFINITIONIn this course, the main evolutionary mechanisms at the molecular and genome levels affecting on the structure of genes, proteins and genomes are described. Molecular phylogenetic methods are included to study level and type of genetic variation at both genome and organismal level and deal with molecular data in order to test evolutionary hypothesis. In this content, this course links to evolutionary thinking to knowledge of molecular biology and genetics.
COURSE CONTENTS
WEEKTOPICS
1st Week Introduction to Molecular Evolution
2nd Week The Molecular Basis of Biology and Evolution
3rd Week Allele Dynamics in Populations
4th Week DNA and Amino Acid Sequence Evolution
5th Week Paper Discussion
6th Week Rates and Patterns of Molecular Evolution
7th Week Molecular Phylogenetics and Phylogenetic Trees
8th Week Midterm Exam
9th Week Reticulate Evolution and Phylogenetic Networks
10th Week Evolution by DNA Duplication
11th Week Paper Discussion
12th Week Evolution by Molecular Tinkering
13th Week Mobile Elements in Evolution
14th Week Eukaryotic Genome Evolution
RECOMENDED OR REQUIRED READINGMolecular and Genome Evolution (2016) (First edition), Graur D., Oxford University Press.
Molecular Evolution, Statistical Approach (2014), Yang, Z., Oxford Scholarships Online.
Integrated Molecular Evolution (2016) (Second Edition), Rogers S.O., CRC Press,Taylor & Francis Group
PLANNED LEARNING ACTIVITIES AND TEACHING METHODSLecture,Discussion,Questions/Answers,Presentation
ASSESSMENT METHODS AND CRITERIA
 QuantityPercentage(%)
Mid-term135
Presentation of Article230
Total(%)65
Contribution of In-term Studies to Overall Grade(%)65
Contribution of Final Examination to Overall Grade(%)35
Total(%)100
ECTS WORKLOAD
Activities Number Hours Workload
Midterm exam122
Preparation for Quiz
Individual or group work
Preparation for Final exam18585
Course hours14342
Preparation for Midterm exam18080
Laboratory (including preparation)
Final exam122
Homework
Presentation (including preperation)24590
Total Workload301
Total Workload / 3010,03
ECTS Credits of the Course10
LANGUAGE OF INSTRUCTIONEnglish
WORK PLACEMENT(S)No
  

KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)
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