At the end of this course, the students; 1) Describe what pharmacology is, talk about the basic principles of pharmacology, tell the pharmaceutical forms of drugs and routes of drug administration, 2) Explain the basic steps of pharmacokinetics by examples, describe the major drug interactions by major mechanisms, to 3) Tell the major factors altering drug effects 4) Talk about the pharmacology of autonomous nervous system, cardiovascular system, central nervous system, and tell the basic pharmacological approach to fluid-electrolyte and acid-base imbalance and intoxications at the basic level at the end of the course.
MODE OF DELIVERY
Face to face
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
None
COURSE DEFINITION
COURSE CONTENTS
WEEK
TOPICS
1st Week
Pharmacology: description and basic principles, administration routes and pharmaceutical forms of drugs
2nd Week
Pharmacokinetics-I: Transfer of drugs across biological membranes and absorption of drugs I-II
3rd Week
Pharmacokinetics-II: Distribution of drugs I-II
4th Week
Pharmacokinetics-III: Biotransformation of drugs I-II
5th Week
Pharmacokinetics-IV: Elimination of drugs I-II
6th Week
Action mechanisms of drugs I-II
7th Week
Drug interactions and the factors altering drug effect I-II
8th Week
Mid-term exam
9th Week
Autonomous nervous system pharmacology I-II
10th Week
Cardiovascular system pharmacology I-II
11th Week
Central nervous system pharmacology I-II
12th Week
Pharmacological approach in the treatment of fluid-electrolyte and acid-base imbalance I-II
13th Week
Pharmacological approach in the treatment of intoxications I-II
14th Week
General review
RECOMENDED OR REQUIRED READING
Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Prof. Dr. S. Oğuz Kayaalp (ed.), 13. baskı, Pelikan Yay. Ltd. Şti., Ankara, 2012 (ISBN: 978-605-5270-10-0). Sağlık Yüksek okulları İçin Farmakoloji, Prof. Dr. İsmet Dökmeci, İstanbul Tıp Kitabevi, İstanbul Medikal Yayıncılık, 2007. Goodman & Gilman's Manual of Pharmacology and Therapeutics, L.L. Brunton, K.L. Parker (editörler), onbirinci baskı, McGraw-Hill, New York, 2008. Goodman & Gilman's The Pharmacological Basis of Therapeutics, L. Brunton, B. Chabner, B. Knollman (editörler), onikinci baskı, McGraw-Hill, New York, 2011. Basic & Clinical Pharmacology, B.G. Katzung, S. B. Masters, A.J. Trevor (editörler), onbirinci baskı, McGraw Hill Lange, 2009. Pharmacology, H.P. Rang, M.M. Dale, J. M. Ritter, R. J. Flower, G. Henderson (editörler), yedinci baskı, Churchill Livingstone, Elsevier, İspanya, 2011. Melmon & Morelli's Clinical Pharmacology, S.G. Carruthers, B.B. Hoffman, K.L. Melmon, D.W. Nierenberg (editörler), dördüncü baskı, McGraw-Hill, New York, 2000. Clinical Pharmacology, P.N. Bennett, M. J. Brown (editörler), dokuzuncu baskı, Churchill Livingstone, Elsevier, İspanya, 2003. Avery's Drug Treatment, T.M. Speight ve N.H.G. Holford (editörler), dördüncü baskı, Adis International, Auckland, 1997. Drug Interactions Handbook, K.A. Bachman (editör), Lexi-Comp Inc., Hudson-Ohio, 2003. BNF/TİK-6 Türkiye İlaç Kılavuzu-2011-12 Formüleri, S.Oğuz Kayaalp (ed.), Pelikan Yayıncılık, Ankara, 2011. Netter's Illustrated Pharmacology, R.B. Baffa, Rawls S.M., Beyzarov E.P. (editörler), Icon Learning Systems, A.B.D., 2005. Pharmacology, G.M. Brenner ve C. W. Stevens (editörler), üçüncü baskı, Saunders Elsevier, Philadelphia, A.B.D., 2010.
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
Lecture,Discussion,Questions/Answers
ASSESSMENT METHODS AND CRITERIA
Quantity
Percentage(%)
Mid-term
1
40
Quiz
1
10
Total(%)
50
Contribution of In-term Studies to Overall Grade(%)
50
Contribution of Final Examination to Overall Grade(%)
50
Total(%)
100
ECTS WORKLOAD
Activities
Number
Hours
Workload
Midterm exam
1
2
2
Preparation for Quiz
Individual or group work
Preparation for Final exam
1
30
30
Course hours
14
2
28
Preparation for Midterm exam
1
25
25
Laboratory (including preparation)
Final exam
1
2
2
Homework
1
3
3
Total Workload
90
Total Workload / 30
3
ECTS Credits of the Course
3
LANGUAGE OF INSTRUCTION
Turkish
WORK PLACEMENT(S)
No
KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)