| TYPE OF COURSE UNIT | Elective Course |
| LEVEL OF COURSE UNIT | Bachelor's Degree |
| YEAR OF STUDY | - |
| SEMESTER | - |
| NUMBER OF ECTS CREDITS ALLOCATED | 4 |
| NAME OF LECTURER(S) | Assistant Professor Aliye Ezgi Güleç Taşkıran
|
| LEARNING OUTCOMES OF THE COURSE UNIT |
At the end of this course, the students;
1) Count the phases of the cell cycle.
2) Use the terms of cell cycle phases, metabolisms and checkpoints correctly.
3) Explain the formation processes of programmed and damage-related cell death types.
4) Discuse the cell cycle and death in the context of different pathologies.
5) Discuse drug development methods against cell cycle-derived cancers.
6) Select the most appropriate analysis method and the methods used to analyze cell division and cell death under laboratory conditions.
|
| MODE OF DELIVERY | Face to face |
| PRE-REQUISITES OF THE COURSE | No |
| RECOMMENDED OPTIONAL PROGRAMME COMPONENT | None |
| COURSE DEFINITION | This course aims to enable the student to understand all the cell cycle components and mechanisms and the different mechanisms of cell death. |
| COURSE CONTENTS | | WEEK | TOPICS |
|---|
| 1st Week | Introduction, History and Basic Definitions | | 2nd Week | External Regulators of the Cell Cycle: Growth Factors | | 3rd Week | Internal Regulators of the Cell Cycle: Cyclins | | 4th Week | G1 and G0 Phase | | 5th Week | S and G2 Phase | | 6th Week | Mitosis- Cell Cycle in Stem Cells | | 7th Week | Cell Cycle Checkpoints | | 8th Week | Midterm | | 9th Week | Meiosis | | 10th Week | Mitochondrial Division - Cell Cycle Analysis Techniques | | 11th Week | Cell Death: Apoptosis, Necrosis and Autophagy - Cellular Senescence | | 12th Week | Control of Programmed Cell Death | | 13th Week | Other Cell Death Mechanisms | | 14th Week | Presentations and Discussion |
|
| RECOMENDED OR REQUIRED READING | Cellular Signal Processing: An Introduction to the Molecular Mechanisms of Signal Transduction 2nd Edition. Friedrich Marks, Ursula Klingmüller, Karin Müller-Decker. Garland Science 2017.
Molecular Cell Biology 8th Edition. Harvey Lodish, Arnold Berk , Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon,Kelsey C. Martin. Macmillan Learning 2016. |
| PLANNED LEARNING ACTIVITIES AND TEACHING METHODS | Lecture,Discussion,Presentation |
| ASSESSMENT METHODS AND CRITERIA | | | Quantity | Percentage(%) |
|---|
| Mid-term | 1 | 30 | | Presentation of Article | 1 | 30 | | Total(%) | | 60 | | Contribution of In-term Studies to Overall Grade(%) | | 60 | | Contribution of Final Examination to Overall Grade(%) | | 40 | | Total(%) | | 100 |
|
| ECTS WORKLOAD |
| Activities |
Number |
Hours |
Workload |
| Midterm exam | 1 | 2 | 2 | | Preparation for Quiz | | | | | Individual or group work | 14 | 1 | 14 | | Preparation for Final exam | 1 | 30 | 30 | | Course hours | 13 | 3 | 39 | | Preparation for Midterm exam | 1 | 20 | 20 | | Laboratory (including preparation) | | | | | Final exam | 1 | 2 | 2 | | Homework | | | | | Article Presentation | 1 | 15 | 15 | | Total Workload | | | 122 |
|---|
| Total Workload / 30 | | | 4,06 |
|---|
| ECTS Credits of the Course | | | 4 |
|---|
|
| LANGUAGE OF INSTRUCTION | Turkish |
| WORK PLACEMENT(S) | No |
| | |
