TYPE OF COURSE UNIT	Elective Course
LEVEL OF COURSE UNIT	Bachelor's Degree
YEAR OF STUDY	-
SEMESTER	-
NUMBER OF ECTS CREDITS ALLOCATED	4
NAME OF LECTURER(S)	-
LEARNING OUTCOMES OF THE COURSE UNIT	At the end of this course, the students; 1) Evaluate oxidative stress formation processes by learning basic information about free radicals. 2) Evaluate the mechanisms of the antioxidative defense system in response to free radicals by learning the basic information about antioxidants. 3) Interpret the oxidative damage status in biological systems using the knowledge learned about the measurement methods of reactive species. 4) Interpret the relationship of nutrition, disease and aging processes with free radicals and antioxidants.
MODE OF DELIVERY	Face to face
PRE-REQUISITES OF THE COURSE	No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT	None
COURSE DEFINITION	This course aims to understand oxidative stress and antioxidant defense mechanisms in biological systems, as well as their relationship with diseases and aging, by providing basic information about free radicals and antioxidants.
COURSE CONTENTS	WEEK TOPICS 1st Week Introduction to the course and general concepts of the course 2nd Week Free radicals 3rd Week Basic principles of oxidative stress 4th Week Oxidative damage mechanisms at cellular level-I: effects on DNA and RNA 5th Week Oxidative damage mechanisms at cellular level-II: effects on lipids and proteins 6th Week Antioxidants synthesized in vivo 7th Week Antioxidants from the diet 8th Week Midterm Exam 9th Week Measurement of reactive species 10th Week Reactive species: special problems and solutions 11th Week Reactive species in disease 12th Week Role for antioxidants in ageing, nutrition, disease, and therapy 13th Week Paper Presentation-I 14th Week Paper Presentation-II
RECOMENDED OR REQUIRED READING	Free Radicals in Biology and Medicine. Barry Halliwell and John M. C. Gutteridge. Fifth Edition. Oxford University Press. 2015. Oxidative Stress and the Molecular Biology of Antioxidant Defences, J. G. Scandolios, Cold Springer Harbour, NY, 1997. Research articles.
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS	Lecture,Discussion,Presentation
ASSESSMENT METHODS AND CRITERIA	Quantity Percentage(%) Mid-term 1 45 Total(%) 45 Contribution of In-term Studies to Overall Grade(%) 45 Contribution of Final Examination to Overall Grade(%) 55 Total(%) 100
ECTS WORKLOAD	Activities Number Hours Workload Midterm exam 1 2 2 Preparation for Quiz Individual or group work 1 10 10 Preparation for Final exam 1 35 35 Course hours 13 3 39 Preparation for Midterm exam 1 30 30 Laboratory (including preparation) Final exam 1 2 2 Homework Article Presentation Total Workload 118 Total Workload / 30 3,93 ECTS Credits of the Course 4
LANGUAGE OF INSTRUCTION	Turkish
WORK PLACEMENT(S)	No