At the end of this course, the students; 1) Explain the scope of bioinformatics, biological databases, basic principles of sequence alignment and similarity scanning in databases and basic algorithms. 2) Analyzes and interprets the prediction of regulatory regions. 3) Explain protein structure analysis and three-dimensional prediction methods. 4) Knows gene expression analysis and interprets the results. 5) Analyzes the relationships between genes or proteins with network biology. 6) Interpret data by learning genome mapping and comparison analysis.
MODE OF DELIVERY
Face to face
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
None
COURSE DEFINITION
Bioinformatics is the synthesis of the fields of mathematics, statistics, computer science, molecular biology and genetics in order to make sense, storage, visualization of biological data and make the most of this huge knowledge. Another definition is the science of compiling and analyzing complex biological data.
COURSE CONTENTS
WEEK
TOPICS
1st Week
Definition and Content of Bioinformatics
2nd Week
Biological Databases
3rd Week
Sequence Alignment
4th Week
Similarity Search in Databases
5th Week
Basic Algorithms
6th Week
Gene Prediction
7th Week
Promotor and Regulatory Sequence Prediction
8th Week
Midterm Exam
9th Week
Phylogenetic TreesProtein Structure Analysis and 3D Prediction
10th Week
Gene Expression Analysis
11th Week
Non-coding RNA Analysis
12th Week
Network Biology
13th Week
Genome Mapping, Assembly, and Comparison
14th Week
Discussion
RECOMENDED OR REQUIRED READING
Essential Bioinformatics, Jin Xiong. Cambridge University Press, 2006. Bioinformatics For Biologists, Pavel Pevzner and Ron Shamir, Cambridge University Press, 2011. Essentials of Bioinformatics, Volume I, Understanding Bioinformatics: Genes to Proteins, Editors: Shaik, N.A., Hakeem, K.R., Banaganapalli, B., Elango, R. Springer, 2019.
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
Lecture,Discussion,Practice,Questions/Answers
ASSESSMENT METHODS AND CRITERIA
Quantity
Percentage(%)
Mid-term
1
35
Assignment
12
10
Project
1
15
Total(%)
60
Contribution of In-term Studies to Overall Grade(%)
60
Contribution of Final Examination to Overall Grade(%)
40
Total(%)
100
ECTS WORKLOAD
Activities
Number
Hours
Workload
Midterm exam
1
2
2
Preparation for Quiz
Individual or group work
Preparation for Final exam
1
30
30
Course hours
13
2
26
Preparation for Midterm exam
1
25
25
Laboratory (including preparation)
Final exam
1
2
2
Homework
12
3
36
Project
1
8
8
Performance Practice
13
2
26
Total Workload
155
Total Workload / 30
5,16
ECTS Credits of the Course
5
LANGUAGE OF INSTRUCTION
Turkish
WORK PLACEMENT(S)
No
KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)