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COURSE UNIT TITLECOURSE UNIT CODESEMESTERTHEORY + PRACTICE (Hour)ECTS
ADVANCED MATHEMATICAL PHYSIOLOGY BME537 - 3 + 0 10

TYPE OF COURSE UNITElective Course
LEVEL OF COURSE UNITMaster's Degree With Thesis
YEAR OF STUDY-
SEMESTER-
NUMBER OF ECTS CREDITS ALLOCATED10
NAME OF LECTURER(S)-
LEARNING OUTCOMES OF THE COURSE UNIT At the end of this course, the students;
1) have knowledge about bioelectrical properties of cell membrane.
2) have knowledge about the action potential.
3) have knowledge about the electrophysiology of the heart.
4) have knowledge about the electrical field of the brain.
5) have knowledge about intra-body properties measurement.
MODE OF DELIVERYFace to face
PRE-REQUISITES OF THE COURSENo
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
COURSE DEFINITION
COURSE CONTENTS
WEEKTOPICS
1st Week Vectors, gradients, divergence. Electrical field and mathematical relations
2nd Week Bioelectrical Properties of Cell Membrane. Transmembrane potential, Ion channels, Ion pumps, Donnan equation, Goldman equation
3rd Week Action Potential
4th Week Active behavior of the membrane. Voltage clamping method. Hodkin-Huxley model;
5th Week Mathematical representation of action potential propagation
6th Week Bioelectrical Relationship of Extracellular Areas. Extracellular potentials. Maxwell's equality
7th Week Electrophysiology of the heart. Electrical transmission of the heart, Einthoven vector, the basis of electrocardiography (ECG)
8th Week Midterm
9th Week ECG. Clinical electrocardiography. ECG measurement methods. Advanced problem solutions in ECG
10th Week Electrical Field of the Brain. Potential changes in the brain. Electroencephalography (EEG). EEG measurement methods and their properties
11th Week Biomagnetic. Magnetostatic equations. Measurement of magnetic flux density. Magnetocardiography (MCG) and Magnetoencephalography (MEG)
12th Week Biomagnetic. Magnetostatic equations. Measurement of magnetic flux density. Magnetocardiography (MCG) and Magnetoencephalography (MEG)
13th Week Measurement of intra-body properties. Performing electrical impedance imaging with various current and voltage applications. Measurement of magnetic precision
14th Week Measurement of intra-body properties. Performing electrical impedance imaging with various current and voltage applications. Measurement of magnetic precision
RECOMENDED OR REQUIRED READING(1) R. Plonsey, R. C. Barr, Bioelectricity, 1988, Plenum Press, New York
(2) Mathematical Physiology/Human Physiology/VANDER
(3) R. Plonsey and David G. Fleming, Bioelectric Phenomena, McGraw-Hill Book Company, 1969.
PLANNED LEARNING ACTIVITIES AND TEACHING METHODSLecture,Presentation,Project
ASSESSMENT METHODS AND CRITERIA
 QuantityPercentage(%)
Mid-term130
Project130
Total(%)60
Contribution of In-term Studies to Overall Grade(%)60
Contribution of Final Examination to Overall Grade(%)40
Total(%)100
ECTS WORKLOAD
Activities Number Hours Workload
Midterm exam17272
Preparation for Quiz000
Individual or group work236
Preparation for Final exam12424
Course hours14342
Preparation for Midterm exam12424
Laboratory (including preparation)000
Final exam19696
Homework
Project12424
Total Workload288
Total Workload / 309,6
ECTS Credits of the Course10
LANGUAGE OF INSTRUCTIONTurkish
WORK PLACEMENT(S)No
  

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