| TYPE OF COURSE UNIT | Elective Course |
| LEVEL OF COURSE UNIT | Master's Degree With Thesis |
| YEAR OF STUDY | - |
| SEMESTER | - |
| NUMBER OF ECTS CREDITS ALLOCATED | 10 |
| NAME OF LECTURER(S) | -
|
| LEARNING OUTCOMES OF THE COURSE UNIT |
At the end of this course, the students;
1) Learn human genetics and genetic disorders
2) Learn inheritance patterns of genetic diseases and molecular mechanisms of hereditary diseases
3) Learn GWAS, functional genomics and single-cell genomic technologies used in human genetics
|
| MODE OF DELIVERY | Face to face |
| PRE-REQUISITES OF THE COURSE | No |
| RECOMMENDED OPTIONAL PROGRAMME COMPONENT | Genetics |
| COURSE DEFINITION | In this course, human genetics and genetic disorders, heritability modes of genetic diseases, molecular mechanisms of inherited diseases, GWAS, functional genomics, and single-cell genomics technologies used in human genetics studies are covered. Students are required to discuss recent research articles in the area. |
| COURSE CONTENTS | | WEEK | TOPICS |
|---|
| 1st Week | Introduction to human genetics | | 2nd Week | Structure of DNA, RNA and protein | | 3rd Week | Molecular mechanisms (replication, transcription, translation, genetic code) | | 4th Week | Regulation of gene function and DNA repair mechanisms | | 5th Week | Human genome organization and chromosomal organization | | 6th Week | Mendelian and Non-mendelian inheritance | | 7th Week | Molecular basis of hereditary diseases and molecular disorders | | 8th Week | Midterm | | 9th Week | Genetic classification of diseases (chromosomal and single gene disorders) | | 10th Week | Genomics, Proteomics and Functional Genomic Technologies | | 11th Week | Gene therapy methods | | 12th Week | Functional genomics technology | | 13th Week | Single-cell technologies | | 14th Week | Student Presentations and Discussion on Articles |
|
| RECOMENDED OR REQUIRED READING | Human Molecular Genetics (5th Edition), Tom Strachan, Andrew Read, Garland Science, 2018.
Recent articles |
| PLANNED LEARNING ACTIVITIES AND TEACHING METHODS | Presentation,Lecture,Discussion,Questions/Answers |
| ASSESSMENT METHODS AND CRITERIA | | | Quantity | Percentage(%) |
|---|
| Mid-term | 1 | 25 | | Presentation of Article | 1 | 20 | | Presentation of Case Study | 1 | 10 | | Total(%) | | 55 | | Contribution of In-term Studies to Overall Grade(%) | | 55 | | Contribution of Final Examination to Overall Grade(%) | | 45 | | Total(%) | | 100 |
|
| ECTS WORKLOAD |
| Activities |
Number |
Hours |
Workload |
| Midterm exam | 1 | 3 | 3 | | Preparation for Quiz | | | | | Individual or group work | | | | | Preparation for Final exam | 1 | 100 | 100 | | Course hours | 14 | 3 | 42 | | Preparation for Midterm exam | 1 | 80 | 80 | | Laboratory (including preparation) | | | | | Final exam | 1 | 3 | 3 | | Homework | | | | | Presentation (including preperation) | 1 | 30 | 30 | | Article Presentation | 1 | 45 | 45 | | Total Workload | | | 303 |
|---|
| Total Workload / 30 | | | 10,1 |
|---|
| ECTS Credits of the Course | | | 10 |
|---|
|
| LANGUAGE OF INSTRUCTION | English |
| WORK PLACEMENT(S) | No |
| | |
