| TYPE OF COURSE UNIT | Elective Course |
| LEVEL OF COURSE UNIT | Master's Degree With Thesis |
| YEAR OF STUDY | - |
| SEMESTER | - |
| NUMBER OF ECTS CREDITS ALLOCATED | 10 |
| NAME OF LECTURER(S) | Assistant Professor Aliye Ezgi Güleç Taşkıran
|
| LEARNING OUTCOMES OF THE COURSE UNIT |
At the end of this course, the students;
1) Know the factors damaging the DNA and their mechanism of action
2) Know the mechanisms the cell evolved against these factors
3) Learn how accumulating damages in the cell cause genomic instability and learn the impact of the genomic stability on the cell survival and physiology
4) Learn new technologies in DNA repair and genomic instability fields
5) Students will be able to read and critically assess research papers relevant to the field of DNA repair and genome instability
|
| MODE OF DELIVERY | Face to face |
| PRE-REQUISITES OF THE COURSE | No |
| RECOMMENDED OPTIONAL PROGRAMME COMPONENT | No |
| COURSE DEFINITION | To investigate different DNA damage responses of the cell to protect its genomic stability, when it encounters DNA damage. |
| COURSE CONTENTS | | WEEK | TOPICS |
|---|
| 1st Week | Introduction-DNA damage | | 2nd Week | Cell cycle and checkpoints | | 3rd Week | Transcription | | 4th Week | Base excision repair, mismatch repair | | 5th Week | Nucleotide excision repair | | 6th Week | Double strand break repair | | 7th Week | DNA damage bypass | | 8th Week | Midterm Exam | | 9th Week | Apoptosis and genomic instability | | 10th Week | Research paper presentation | | 11th Week | Research paper presentation | | 12th Week | Research paper presentation | | 13th Week | Research paper presentation | | 14th Week | Research paper presentation |
|
| RECOMENDED OR REQUIRED READING | Alberts, The Cell, 6th Edition
Recent articles
|
| PLANNED LEARNING ACTIVITIES AND TEACHING METHODS | Lecture,Discussion,Questions/Answers,Presentation,Case Study,Problem Solving |
| ASSESSMENT METHODS AND CRITERIA | | | Quantity | Percentage(%) |
|---|
| Mid-term | 1 | 40 | | Attendance | 1 | 10 | | Total(%) | | 50 | | Contribution of In-term Studies to Overall Grade(%) | | 50 | | Contribution of Final Examination to Overall Grade(%) | | 50 | | Total(%) | | 100 |
|
| ECTS WORKLOAD |
| Activities |
Number |
Hours |
Workload |
| Midterm exam | 1 | 3 | 3 | | Preparation for Quiz | | | | | Individual or group work | 14 | 2 | 28 | | Preparation for Final exam | 1 | 125 | 125 | | Course hours | 13 | 3 | 39 | | Preparation for Midterm exam | 1 | 100 | 100 | | Laboratory (including preparation) | | | | | Final exam | 1 | 3 | 3 | | Homework | | | | | Total Workload | | | 298 |
|---|
| Total Workload / 30 | | | 9,93 |
|---|
| ECTS Credits of the Course | | | 10 |
|---|
|
| LANGUAGE OF INSTRUCTION | English |
| WORK PLACEMENT(S) | No |
| | |
