TYPE OF COURSE UNIT	Elective Course
LEVEL OF COURSE UNIT	Master's Degree With Thesis
YEAR OF STUDY	-
SEMESTER	-
NUMBER OF ECTS CREDITS ALLOCATED	10
NAME OF LECTURER(S)	-
LEARNING OUTCOMES OF THE COURSE UNIT	At the end of this course, the students; 1) learn gene delivery systems and methods. 2) undertand and discuss the gene therapy approaches and starategies. 3) learn the generation of transgenics and transgene analysis. 4) learn and discuss the application areas of transgenics.
MODE OF DELIVERY	Face to face
PRE-REQUISITES OF THE COURSE	No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT	Research Techniques for Molecular Biology and Genetics, Recombinant DNA Technology, Genetic Engineering
COURSE DEFINITION	This course covers information about requirements for gene expression in prokaryotes and eukaryotes, methods and techniques used to manipulate DNA, gene transfer methodologies, strategies for identifying and analyzing transgene, generation process of transgenic animals, the importance of transgenics in medicine and biotechnology, gene therapy applications, and current approaches to gene therapy.
COURSE CONTENTS	WEEK TOPICS 1st Week The history of gene therapy 2nd Week Genetic manipulation 3rd Week Gene transfer strategies 4th Week Somatic gene therapy 5th Week Germline gene therapy 6th Week Applications and advances in gene therapy 7th Week Ethical Issues in human gene transfer research 8th Week Midterm Exam 9th Week Transgenic animals 10th Week Production of transgenic animals 11th Week Analysis of transgene expression 12th Week Applications of transgenic animals in medicine 13th Week Applications of transgenic animals in biotechnology 14th Week Student presentations
RECOMENDED OR REQUIRED READING	Gene Cloning and Analysis: an introduction, 6th Edition. Brown, T.A. 2010. The Development of Human Gene Therapy, Friedman, T. (1999) Cold Spring Harbor, NY: Cold Spring Harbor Lab.Press. Transgenic Mouse: Methods and Protocols, Marten H. Hofker, Jan van Deursen, 2002.
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS	Lecture,Discussion,Questions/Answers,Presentation
ASSESSMENT METHODS AND CRITERIA	Quantity Percentage(%) Assignment 1 30 Project 1 45 Presentation of Article 1 25 Total(%) 100 Contribution of In-term Studies to Overall Grade(%) 100 Contribution of Final Examination to Overall Grade(%) 0 Total(%) 100
ECTS WORKLOAD	Activities Number Hours Workload Midterm exam Preparation for Quiz Individual or group work Preparation for Final exam Course hours 14 3 42 Preparation for Midterm exam Laboratory (including preparation) Final exam Homework 1 50 50 Project 1 175 175 Article Presentation 1 35 35 Total Workload 302 Total Workload / 30 10,06 ECTS Credits of the Course 10
LANGUAGE OF INSTRUCTION	English
WORK PLACEMENT(S)	No