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COURSE UNIT TITLECOURSE UNIT CODESEMESTERTHEORY + PRACTICE (Hour)ECTS
ADVANCED MOLECULAR GENETICS MBGE501 - 3 + 0 10

TYPE OF COURSE UNITElective Course
LEVEL OF COURSE UNITMaster's Degree With Thesis
YEAR OF STUDY-
SEMESTER-
NUMBER OF ECTS CREDITS ALLOCATED10
NAME OF LECTURER(S)Assistant Professor Özge Akbulut Çalışkan
LEARNING OUTCOMES OF THE COURSE UNIT At the end of this course, the students;
1) Learn about recent research on genome structure and organization.
2) Know about recent research on molecular mechanisms of geneexpression.
3) Learn about recent research on regulation of gene expression and functions of small non-coding RNAs.
MODE OF DELIVERYFace to face
PRE-REQUISITES OF THE COURSENo
RECOMMENDED OPTIONAL PROGRAMME COMPONENTMolecular Biology, Molecular Genetis, Recombinant DNA Technology
COURSE DEFINITIONThis course is designed to provide information about recent research on genome structure and organization, the molecular genetics of gene expression and molecular mechanisms of gene regulation. Students will be also engaged in this course to facilitate the students? independent learning capacity, problem solving skills. They will choose and present recent articles that are related to the lecture.
COURSE CONTENTS
WEEKTOPICS
1st Week Introduction
2nd Week Genome Structure and Interrupted Genes
3rd Week The Replicon and DNA Replication
4th Week Transcription and Transcriptional Control in Prokaryotes
5th Week Transcription and Transcriptional Control in Eukaryotes
6th Week Recent Article Presentations
7th Week Recent Article Presentations
8th Week Midterm Exam
9th Week Splicing and Processing
10th Week Translation and Genetic Code
11th Week Translational Control and mRNA Stability
12th Week Non-coding RNAs and Post-translational Regulation Mechanisms
13th Week Recent Article Presentations
14th Week Recent Article Presentations
RECOMENDED OR REQUIRED READING-Lewin?s Genes XII (12th ed.), Jocelyn E. Krebs, Elliott S. Goldstein, Stephen T.
Kilpatrick, Jones & Bartlett Learning, 2018
-Molecular Biology of the Gene (7th ed.), James D. Watson, Tania A. Baker,
Stephen P. Bell, Alexander Gann, Michael Levine, Richard Losick, Pearson,
2013
-Molecular Biology of the Cell (6th ed.), Bruce Alberts, Garland Science, 2017
-Recent articles
PLANNED LEARNING ACTIVITIES AND TEACHING METHODSPresentation,Discussion,Lecture,Questions/Answers
ASSESSMENT METHODS AND CRITERIA
 QuantityPercentage(%)
Mid-term125
Attendance15
Presentation of Article230
Total(%)60
Contribution of In-term Studies to Overall Grade(%)60
Contribution of Final Examination to Overall Grade(%)40
Total(%)100
ECTS WORKLOAD
Activities Number Hours Workload
Midterm exam133
Preparation for Quiz
Individual or group work
Preparation for Final exam19595
Course hours14342
Preparation for Midterm exam18080
Laboratory (including preparation)
Final exam133
Homework
Presentation (including preperation)24080
Article Presentation2,751,5
Total Workload304,5
Total Workload / 3010,15
ECTS Credits of the Course10
LANGUAGE OF INSTRUCTIONEnglish
WORK PLACEMENT(S)No
  

KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)
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