| TYPE OF COURSE UNIT | Elective Course |
| LEVEL OF COURSE UNIT | Bachelor's Degree |
| YEAR OF STUDY | - |
| SEMESTER | - |
| NUMBER OF ECTS CREDITS ALLOCATED | 4 |
| NAME OF LECTURER(S) | -
|
| LEARNING OUTCOMES OF THE COURSE UNIT |
At the end of this course, the students;
1) Learn the concepts and general information about pharmacogenetics.
2) Learn the pathways of drug metabolism.
3) Understand the mechanisms changing the action and bioavailability of drugs at the molecular level.
4) Learn the genetic characteristics changing the effects of the drugs used for treatment and diagnosis.
|
| MODE OF DELIVERY | Face to face |
| PRE-REQUISITES OF THE COURSE | No |
| RECOMMENDED OPTIONAL PROGRAMME COMPONENT | None |
| COURSE DEFINITION | The aim of this study is to discuss the changes in drug kinetics and the response of patients to drugs between individuals and ethnic groups according to genetic structure. |
| COURSE CONTENTS | | WEEK | TOPICS |
|---|
| 1st Week | Introduction to pharmacogenetics | | 2nd Week | Genetics and epigenetics in drug therapy | | 3rd Week | Drug Metabolism I | | 4th Week | Drug Metabolism II | | 5th Week | Pharmacogenetics of drug transporters | | 6th Week | Pharmacogenetics of drug targets | | 7th Week | Pharmacogenetics in cancer | | 8th Week | MIDTERM | | 9th Week | Pharmacogenetics in other disease | | 10th Week | High-throughput genotyping technologies for pharmacogenetic | | 11th Week | Modeling drug response | | 12th Week | Drug discovery | | 13th Week | Ethical and social issues in pharmacogenomics researching | | 14th Week | Pharmacogenetics: industry and regulatory affairs |
|
| RECOMENDED OR REQUIRED READING | Pharmacogenetics And Individualized Therapy. Anke-Hilse Maitland-van der Zee, Ann K. Daly. Wiley Press. 2012.
Rang and Dale s Pharmacology, 7th. Edition, 2011.
The Cell: A Molecular Approach, Geoffrey M. Cooper and Robert E. Hausman, 5th Edition, 2009. |
| PLANNED LEARNING ACTIVITIES AND TEACHING METHODS | Lecture,Questions/Answers,Presentation |
| ASSESSMENT METHODS AND CRITERIA | | | Quantity | Percentage(%) |
|---|
| Mid-term | 1 | 35 | | Assignment | 1 | 10 | | Attendance | 1 | 5 | | Total(%) | | 50 | | Contribution of In-term Studies to Overall Grade(%) | | 50 | | Contribution of Final Examination to Overall Grade(%) | | 50 | | Total(%) | | 100 |
|
| ECTS WORKLOAD |
| Activities |
Number |
Hours |
Workload |
| Midterm exam | 1 | 2 | 2 | | Preparation for Quiz | | | | | Individual or group work | 14 | 1 | 14 | | Preparation for Final exam | 1 | 30 | 30 | | Course hours | 13 | 3 | 39 | | Preparation for Midterm exam | 1 | 20 | 20 | | Laboratory (including preparation) | | | | | Final exam | 1 | 2 | 2 | | Homework | 1 | 15 | 15 | | Total Workload | | | 122 |
|---|
| Total Workload / 30 | | | 4,06 |
|---|
| ECTS Credits of the Course | | | 4 |
|---|
|
| LANGUAGE OF INSTRUCTION | Turkish |
| WORK PLACEMENT(S) | No |
| | |
