| TYPE OF COURSE UNIT | Elective Course |
| LEVEL OF COURSE UNIT | Bachelor's Degree |
| YEAR OF STUDY | - |
| SEMESTER | - |
| NUMBER OF ECTS CREDITS ALLOCATED | 4 |
| NAME OF LECTURER(S) | -
|
| LEARNING OUTCOMES OF THE COURSE UNIT |
At the end of this course, the students;
1) Learn basic principles of human genetics and genetic disorders.
2) Understand the heritability modes of genetic diseases.
3) Learn the molecular mechanisms of inherited diseases and methods of gene therapies.
4) Learn the moleculer methods used in detection of genes responsible for inherired diseases.
5) Understand the molecular and metabolic mechanisms of inherited diseases.
|
| MODE OF DELIVERY | Face to face |
| PRE-REQUISITES OF THE COURSE | No |
| RECOMMENDED OPTIONAL PROGRAMME COMPONENT | None |
| COURSE DEFINITION | Genetic diseases course aims to provide information on family tree and inheritance patterns, mechanisms of chromosomal aberrations, single gene diseases (commonly observed and genetic approach), non-Mendelian inheritance and molecular approach treatment methods for genetic diseases. |
| COURSE CONTENTS | | WEEK | TOPICS |
|---|
| 1st Week | Basic genetic concepts | | 2nd Week | Inheritance types | | 3rd Week | Mendelian inheritance | | 4th Week | Single gene inheritance: Autosomal inheritance | | 5th Week | Single gene inheritance: Sex-linked inheritance | | 6th Week | Multifactorial inheritance | | 7th Week | Mitocondrial inheritance | | 8th Week | MIDTERM | | 9th Week | Nonmendelian inheritance | | 10th Week | Mechanisms of genetic diseases: Biochemical and genetic mechanisms | | 11th Week | Mechanisms of genetic diseases: Triple repeat disease | | 12th Week | Identification of genes responsible for hereditary diseases | | 13th Week | Treatment of metabolic anomalies and treatment of protein levels | | 14th Week | Treatment with gene expression control and gene therapy |
|
| RECOMENDED OR REQUIRED READING | Molecular basis of inherited disease. 2nd ed. K.E. Davies, A.P. Read. Oxford, 1992.
An Introduction to Human Molecular Genetic: Mechanisms of Inherited Diseases, 2nd Edition, Jack J. Pasternak. Wiley, 2005. |
| PLANNED LEARNING ACTIVITIES AND TEACHING METHODS | Lecture,Questions/Answers,Presentation |
| ASSESSMENT METHODS AND CRITERIA | | | Quantity | Percentage(%) |
|---|
| Mid-term | 1 | 35 | | Assignment | 1 | 10 | | Attendance | 1 | 5 | | Total(%) | | 50 | | Contribution of In-term Studies to Overall Grade(%) | | 50 | | Contribution of Final Examination to Overall Grade(%) | | 50 | | Total(%) | | 100 |
|
| ECTS WORKLOAD |
| Activities |
Number |
Hours |
Workload |
| Midterm exam | 1 | 2 | 2 | | Preparation for Quiz | | | | | Individual or group work | 14 | 1 | 14 | | Preparation for Final exam | 1 | 30 | 30 | | Course hours | 13 | 3 | 39 | | Preparation for Midterm exam | 1 | 20 | 20 | | Laboratory (including preparation) | | | | | Final exam | 1 | 2 | 2 | | Homework | 1 | 15 | 15 | | Total Workload | | | 122 |
|---|
| Total Workload / 30 | | | 4,06 |
|---|
| ECTS Credits of the Course | | | 4 |
|---|
|
| LANGUAGE OF INSTRUCTION | Turkish |
| WORK PLACEMENT(S) | No |
| | |
