At the end of this course, the students; 1) Defines and exemplifies intracellular metabolic processes. 2) Based on the concepts of bioenergetics, makes energy calculations in metabolism. 3) Explain and write the breakdown and synthesis reactions of carbohydrates, lipids, proteins and nucleic acids. 4) Knowing the clinical importance of enzymes involved in metabolic processes, writes the connection with diseases by explaining a cause-effect relationship.
MODE OF DELIVERY
Face to face
PRE-REQUISITES OF THE COURSE
No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT
None
COURSE DEFINITION
The aim of this course is to enable students to gain an understanding of basics of metabolic process and transportation systems in the cell.
COURSE CONTENTS
WEEK
TOPICS
1st Week
Glycolysis
2nd Week
Citric Acid Cycle
3rd Week
Electron Transport Chain
4th Week
Oxidative Phosphorylation and Control of ATP Production
5th Week
Glycogen Metabolism
6th Week
Gluconeogenesis
7th Week
Catabolism of Other Carbohydrates
8th Week
Midterm Exam
9th Week
Lipid Catabolism
10th Week
Lipid Anabolism
11th Week
Amino Acid Metabolism I
12th Week
Amino Acid Metabolism II
13th Week
Nucleotide Metabolism I
14th Week
Nucleotide Metabolism II
RECOMENDED OR REQUIRED READING
Lehninger Principles of Biochemistry. David L. Nelson, Michael M. Cox. W.H. Freeman, 7th Edition, 2017. Fundamentals of Biochemistry: Life at the Molecular Level. Donald Voet, Judith G. Voet, Charlotte W. Pratt. Wiley, 5th Edition, 2016. Biochemistry. Christopher K. Mathews, Kensal E. van Holde, Dean R. Appling, Spencer J. Anthony-Cahill, Pearson 4th Edition, 2012.
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS
Lecture,Questions/Answers,Discussion
ASSESSMENT METHODS AND CRITERIA
Quantity
Percentage(%)
Mid-term
1
30
Assignment
1
20
Quiz
4
15
Total(%)
65
Contribution of In-term Studies to Overall Grade(%)
65
Contribution of Final Examination to Overall Grade(%)
35
Total(%)
100
ECTS WORKLOAD
Activities
Number
Hours
Workload
Midterm exam
1
2
2
Preparation for Quiz
4
3
12
Individual or group work
14
2
28
Preparation for Final exam
1
15
15
Course hours
13
3
39
Preparation for Midterm exam
1
10
10
Laboratory (including preparation)
Final exam
1
2
2
Homework
1
10
10
Quiz
4
,5
2
Total Workload
120
Total Workload / 30
4
ECTS Credits of the Course
4
LANGUAGE OF INSTRUCTION
Turkish
WORK PLACEMENT(S)
No
KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)