| TYPE OF COURSE UNIT | Elective Course |
| LEVEL OF COURSE UNIT | Bachelor's Degree |
| YEAR OF STUDY | - |
| SEMESTER | - |
| NUMBER OF ECTS CREDITS ALLOCATED | 4 |
| NAME OF LECTURER(S) | Professor Özlem Darcansoy İşeri
|
| LEARNING OUTCOMES OF THE COURSE UNIT |
At the end of this course, the students;
1) Understand basic molecular mechanisms and data processing of signal transduction.
2) Learn extracellular signals, cell receptors and secondary messengers.
3) Learn sensory signal processing and signaling at synapses.
4) Discuss basic signal transduction processes in relation to different pathological conditions.
|
| MODE OF DELIVERY | Face to face |
| PRE-REQUISITES OF THE COURSE | No |
| RECOMMENDED OPTIONAL PROGRAMME COMPONENT | None |
| COURSE DEFINITION | In this course, intercellular communications, intracellular signal transduction pathways, and participation of these pathways in specific pathophysiologies are given. |
| COURSE CONTENTS | | WEEK | TOPICS |
|---|
| 1st Week | Introduction to and Networks of Cell | | 2nd Week | Molecular Switches | | 3rd Week | Signal Transduction by G-Protein-Coupled Receptors and Secondary Messengers I | | 4th Week | Signal Transduction by G-Protein-Coupled Receptors and Secondary Messengers II | | 5th Week | Signal Transduction by Tyrosine Kinase and Secondary Messengers I | | 6th Week | Signal Transduction by Tyrosine Kinase and Secondary Messengers II | | 7th Week | Nuclear Receptors | | 8th Week | Midterm Exam | | 9th Week | Controlled Proteolysis and Signal Transduction | | 10th Week | Sensory Signaling Pathways I | | 11th Week | Sensory Signaling Pathways II | | 12th Week | Circadian Rhythm | | 13th Week | Discussion in Relation to Pathological Conditions | | 14th Week | Discussion in Relation to Pathological Conditions |
|
| RECOMENDED OR REQUIRED READING | Cellular Signal Processing: An Introduction to the Molecular Mechanisms of Signal Transduction 2nd Edition. Friedrich Marks, Ursula Klingmüller, Karin Müller-Decker. Garland Science 2017.
Cell Signaling: Principles and Mechanisms. 1st Edition. Lim, Mayer, Pawson. Garland Science 2017.
Molecular Biology of the Cell. 6th edition. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter.
|
| PLANNED LEARNING ACTIVITIES AND TEACHING METHODS | Lecture,Discussion,Questions/Answers,Presentation |
| ASSESSMENT METHODS AND CRITERIA | | | Quantity | Percentage(%) |
|---|
| Mid-term | 1 | 30 | | Presentation of Article | 1 | 20 | | Total(%) | | 50 | | Contribution of In-term Studies to Overall Grade(%) | | 50 | | Contribution of Final Examination to Overall Grade(%) | | 50 | | Total(%) | | 100 |
|
| ECTS WORKLOAD |
| Activities |
Number |
Hours |
Workload |
| Midterm exam | 1 | 2 | 2 | | Preparation for Quiz | | | | | Individual or group work | 14 | 1 | 14 | | Preparation for Final exam | 1 | 25 | 25 | | Course hours | 13 | 3 | 39 | | Preparation for Midterm exam | 1 | 22 | 22 | | Laboratory (including preparation) | | | | | Final exam | 1 | 2 | 2 | | Homework | | | | | Article Presentation | 1 | 16 | 16 | | Total Workload | | | 120 |
|---|
| Total Workload / 30 | | | 4 |
|---|
| ECTS Credits of the Course | | | 4 |
|---|
|
| LANGUAGE OF INSTRUCTION | Turkish |
| WORK PLACEMENT(S) | No |
| | |
