TYPE OF COURSE UNIT	Elective Course
LEVEL OF COURSE UNIT	Master's Degree Without Thesis
YEAR OF STUDY	-
SEMESTER	-
NUMBER OF ECTS CREDITS ALLOCATED	10
NAME OF LECTURER(S)	-
LEARNING OUTCOMES OF THE COURSE UNIT	At the end of this course, the students; 1) To get information about conventional dosage forms and controlled release systems. 2) To learn classification of cntrolled release systems based on their release mechanisms and drug delivery systems based on their application routes. 3) To learn active and pasive drug targetting and novelities in controlled release systems with their places/importancies through the drug sector. 4) Literature research and experimental design.
MODE OF DELIVERY	Face to face
PRE-REQUISITES OF THE COURSE	No
RECOMMENDED OPTIONAL PROGRAMME COMPONENT	NO
COURSE DEFINITION	To introduce drug delivery systems, drug targeting techniques and applications that are being developed to eliminate the disadvantages of traditional dosage forms that have been used from past to present in drug and active substances and therapeutic applications, and to provide the necessary knowledge on these issues.
COURSE CONTENTS	WEEK TOPICS 1st Week 1) Basic definitions and information about active pharmaceutical ingredients and their transport. 2nd Week 2) Comparison of the advantages and disadvantages of conventional dosage forms and controlled release systems. 3rd Week 3) Classification of controlled release systems according to active substance release mechanisms 4th Week 4) Drug targeting systems (active and passive targeting). 5th Week 5) Classification of active substance transport according to administration routes: Oral, buccal and nasal systems 6th Week 6) Classification of active substance transport according to administration routes: Trans-mucosal administered systems 7th Week 7) Classification of active substance transport according to application routes: Transdermal systems 8th Week 8) Classification of active substance transport according to administration routes: Vaginal, cervical and intrauterine systems 9th Week 9) Classification of active substance transport according to administration routes: Pulmonary systems 10th Week 10) Classification of active substance transport according to application routes: Opthalmology applications 11th Week 11) Classification of active substance transport according to administration routes: Central nervous system applications 12th Week 12) Current and future applications of controlled release systems: Gene therapies 13th Week 13) Current and future applications of controlled release systems: New generation technologies. 14th Week 14) Economics and market place of controlled release systems. 15th Week 15) Discussion and article presentation 16th Week
RECOMENDED OR REQUIRED READING	1. Li X., Bhaskara R. Jasti B.R., Design of Controlled Release Drug Delivery Systems, McGraw-Hill Co., New York, 2006. 2. Hillery A.M., Llyod A.W., Swarbrick J., Drug Delivery and Targetting for Pharmacists and Pharmaceutical Scientists, Taylor & Francis, 2005. 3. Maskevich B.O., Drug Delivery Research Advances, Nova Science Publishers, Inc. New York, 2007. 4. Ranade V.V., Hollinger M.A., Drug Delivery Systems, 2nd Ed., CRC Press LLC, 2004. 5. De Villiers M.M., Aramwit P., Kwon G.S., Nanotechnology in Drug Delivery, AAPS Springer, 2009. 6. Ottenbrite R.M., Kim S.W., Polymeric Drugs and Drug Delivery, CRC Press LLC, 2001. 7. Uchegbu I. F., Polymers in Drug Delivery, CRC Press 2006. 8. Mitra A.K., Ophthalmic Drug Delivery Systems2nd Ed., Revised and Expanded, Mercel Dekker, NY, 2003. 9. Marx U., Sandig V., Drug Testing In Vitro, WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim, 2007
PLANNED LEARNING ACTIVITIES AND TEACHING METHODS	Lecture,Questions/Answers,Presentation,Other
ASSESSMENT METHODS AND CRITERIA	Quantity Percentage(%) Mid-term 1 30 Project 1 25 Total(%) 55 Contribution of In-term Studies to Overall Grade(%) 55 Contribution of Final Examination to Overall Grade(%) 45 Total(%) 100
ECTS WORKLOAD	Activities Number Hours Workload Midterm exam 1 72 72 Preparation for Quiz 0 0 0 Individual or group work 2 3 6 Preparation for Final exam 1 24 24 Course hours 14 3 42 Preparation for Midterm exam 1 24 24 Laboratory (including preparation) 0 0 0 Final exam 1 96 96 Homework Project 1 24 24 Total Workload 288 Total Workload / 30 9,6 ECTS Credits of the Course 10
LANGUAGE OF INSTRUCTION	Turkish
WORK PLACEMENT(S)	No