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COURSE UNIT TITLECOURSE UNIT CODESEMESTERTHEORY + PRACTICE (Hour)ECTS
MOLECULAR BIOTECHNOLOGY FOR ENGINEERS BME620 - 3 + 0 10

TYPE OF COURSE UNITElective Course
LEVEL OF COURSE UNITDoctorate Of Science
YEAR OF STUDY-
SEMESTER-
NUMBER OF ECTS CREDITS ALLOCATED10
NAME OF LECTURER(S)Professor Özlem Darcansoy İşeri
LEARNING OUTCOMES OF THE COURSE UNIT At the end of this course, the students;
1) To have knowledge on biotechnological products, process concepts and principles
2) To understand the basic principles and applications of genetic manipulation in biotechnology
3) To have knowledge on different cell types and their products
4) To understand omic technologies and their applications
5) To understand basic principles of bioremediation and biomass utilization
6) To discuss current applications of molecular biotechnology in social, ethical and legal perspectives
MODE OF DELIVERYFace to face
PRE-REQUISITES OF THE COURSENo
RECOMMENDED OPTIONAL PROGRAMME COMPONENTNone
COURSE DEFINITIONBiotechnology Market and Biotechnological Products; Basic Principles of Biotechnological Processes Bioreactors and Principles of Cellular Production; Biomolecular Principles from Gene to Protein Basic Principles of Molecular Cloning and Gene Engineering; Recombinant DNA Technology and Heterologous Protein Production Gene Delivery into Cells and Transgenic Organisms; Protein Engineering and Protein Therapeutics Hybridoma Technology and Monoclonal Antibody Production; Omic Technologies; Bioremediation and Biomass Utilization Society, Ethics and Legal Regulations
COURSE CONTENTS
WEEKTOPICS
1st Week Biotechnology Market and Biotechnological Products
2nd Week Process Principles in Biotechnology
3rd Week Bioreactors and Principles of Cellular Production
4th Week Biomolecular Principles from Gene to Protein
5th Week Molecular Cloning and Basic Principles of Genetic Engineering
6th Week Recombinant DNA Technology and Heterologous Protein Production
7th Week Gene Transfer to Cells and Transgenic Organisms
8th Week Midterm Week
9th Week Protein Engineering and Protein Therapeutics
10th Week Hybridoma Technology and Monoclonal Antibody Production
11th Week Omic Technologies
12th Week Bioremediation and Biomass Utilization
13th Week Social, Ethical and Legal Issues
14th Week Presentations
RECOMENDED OR REQUIRED READINGIntroduction to Biotechnology (3rd Edition). William J. Thieman, Michael A. Palladino, Benjamin Cummings Press, 2012.
Molecular Biotechnology, Principles and Applications of Recombinant DNA. Bernard R. Glick, Jack J. Pasternak, ASM Press, Washington, D.C., 2009.
Principles of Gene Manipulation and Genomics, 7th Edition, Sandy B. Primrose, Richard Twyman, Wiley-Blackwell, 2006.
Internet and library files.
PLANNED LEARNING ACTIVITIES AND TEACHING METHODSLecture,Discussion,Presentation
ASSESSMENT METHODS AND CRITERIA
 QuantityPercentage(%)
Mid-term135
Assignment115
Total(%)50
Contribution of In-term Studies to Overall Grade(%)50
Contribution of Final Examination to Overall Grade(%)50
Total(%)100
ECTS WORKLOAD
Activities Number Hours Workload
Midterm exam17272
Preparation for Quiz000
Individual or group work236
Preparation for Final exam12424
Course hours14342
Preparation for Midterm exam12424
Laboratory (including preparation)000
Final exam19696
Homework12424
Total Workload288
Total Workload / 309,6
ECTS Credits of the Course10
LANGUAGE OF INSTRUCTIONEnglish
WORK PLACEMENT(S)No
  

KEY LEARNING OUTCOMES (KLO) / MATRIX OF LEARNING OUTCOMES (LO)
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K3            X
K4  X   X   X   X   X  
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K8            X